Vogt–Koyanagi–Harada syndrome – current perspectives

Abeir Baltmr,1 Sue Lightman,1,2 Oren Tomkins-Netzer1–3 1Uveitis Service, Moorfields Eye Hospital, London, UK; 2Department of Clinical Ophthalmology, UCL Institute of Ophthalmology, London, UK; 3Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel Abstract: Vogt&am...

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Autores principales: Baltmr A, Lightman S, Tomkins-Netzer O
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Publicado: Dove Medical Press 2016
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spelling oai:doaj.org-article:531d7615b2574a3291be735bbb1062812021-12-02T00:23:43ZVogt–Koyanagi–Harada syndrome – current perspectives1177-5483https://doaj.org/article/531d7615b2574a3291be735bbb1062812016-11-01T00:00:00Zhttps://www.dovepress.com/vogtndashkoyanagindashharada-syndrome-ndash-current-perspectives-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Abeir Baltmr,1 Sue Lightman,1,2 Oren Tomkins-Netzer1–3 1Uveitis Service, Moorfields Eye Hospital, London, UK; 2Department of Clinical Ophthalmology, UCL Institute of Ophthalmology, London, UK; 3Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel Abstract: Vogt–Koyanagi–Harada syndrome is a cause of noninfectious panuveitis, leading to significant vision loss in many patients. It is an autoimmune disease occurring in genetically susceptible individuals and clinically presents as bilateral panuveitis with serous retinal detachments and hyperemic, swollen optic discs, which are associated with neurological and auditory manifestations. Early diagnosis and prompt and adequate treatment with immunosuppressive agents (corticosteroids and other immunosuppressive drugs) may halt disease progression and prevent recurrences and vision loss. This review summarizes the current knowledge on the variable clinical aspects of this disease, highlighting diagnostic and treatment strategies. Keywords: multifocal choroiditis, serous retinal detachment, panuveitis, sunset glow fundus, starry sky, corticosteroidBaltmr ALightman STomkins-Netzer ODove Medical PressarticleVogt–Koyanagi–Harada disease (VKH)serous retinal detachmentpanuveitissunset glow fundusstarry skyOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 10, Pp 2345-2361 (2016)
institution DOAJ
collection DOAJ
language EN
topic Vogt–Koyanagi–Harada disease (VKH)
serous retinal detachment
panuveitis
sunset glow fundus
starry sky
Ophthalmology
RE1-994
spellingShingle Vogt–Koyanagi–Harada disease (VKH)
serous retinal detachment
panuveitis
sunset glow fundus
starry sky
Ophthalmology
RE1-994
Baltmr A
Lightman S
Tomkins-Netzer O
Vogt–Koyanagi–Harada syndrome – current perspectives
description Abeir Baltmr,1 Sue Lightman,1,2 Oren Tomkins-Netzer1–3 1Uveitis Service, Moorfields Eye Hospital, London, UK; 2Department of Clinical Ophthalmology, UCL Institute of Ophthalmology, London, UK; 3Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel Abstract: Vogt–Koyanagi–Harada syndrome is a cause of noninfectious panuveitis, leading to significant vision loss in many patients. It is an autoimmune disease occurring in genetically susceptible individuals and clinically presents as bilateral panuveitis with serous retinal detachments and hyperemic, swollen optic discs, which are associated with neurological and auditory manifestations. Early diagnosis and prompt and adequate treatment with immunosuppressive agents (corticosteroids and other immunosuppressive drugs) may halt disease progression and prevent recurrences and vision loss. This review summarizes the current knowledge on the variable clinical aspects of this disease, highlighting diagnostic and treatment strategies. Keywords: multifocal choroiditis, serous retinal detachment, panuveitis, sunset glow fundus, starry sky, corticosteroid
format article
author Baltmr A
Lightman S
Tomkins-Netzer O
author_facet Baltmr A
Lightman S
Tomkins-Netzer O
author_sort Baltmr A
title Vogt–Koyanagi–Harada syndrome – current perspectives
title_short Vogt–Koyanagi–Harada syndrome – current perspectives
title_full Vogt–Koyanagi–Harada syndrome – current perspectives
title_fullStr Vogt–Koyanagi–Harada syndrome – current perspectives
title_full_unstemmed Vogt–Koyanagi–Harada syndrome – current perspectives
title_sort vogt–koyanagi–harada syndrome – current perspectives
publisher Dove Medical Press
publishDate 2016
url https://doaj.org/article/531d7615b2574a3291be735bbb106281
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