Cystoid macular edema secondary to immune recovery uveitis in a man with cytomegalovirus retinitis and AIDS

Kathir YoganathanHIV/Genito-Urinary Medicine, Abertawe Bro Morgannwg University Health Board, Singleton hospital, Swansea, UKAbstract: Cytomegalovirus (CMV) is the most common intraocular opportunistic infection in profoundly immunocompromised patients with AIDS. It is characterized by an acute, pro...

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Autor principal:	Kathir Yoganathan
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2010
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/532107dbae404180ab3450fcdb4a91c0
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spelling	oai:doaj.org-article:532107dbae404180ab3450fcdb4a91c02021-12-02T02:48:11ZCystoid macular edema secondary to immune recovery uveitis in a man with cytomegalovirus retinitis and AIDS1177-54671177-5483https://doaj.org/article/532107dbae404180ab3450fcdb4a91c02010-09-01T00:00:00Zhttp://www.dovepress.com/cystoid-macular-edema-secondary-to-immune-recovery-uveitis-in-a-man-wi-a5334https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Kathir YoganathanHIV/Genito-Urinary Medicine, Abertawe Bro Morgannwg University Health Board, Singleton hospital, Swansea, UKAbstract: Cytomegalovirus (CMV) is the most common intraocular opportunistic infection in profoundly immunocompromised patients with AIDS. It is characterized by an acute, progressive, necrotizing retinitis in patients with a CD4 count of &lt;50 cells/&micro;L. Although the incidence of CMV retinitis has declined because of the introduction of antiretroviral therapy (ART), a new syndrome of intraocular inflammation has emerged in patients with rising CD4 lymphocyte counts following ART. This is called immune recovery uveitis (IRU). It is thought to occur as a result of restored immunity to various infectious agents, commonly mycobacterial, Cryptococcus, and herpes virus infections. We report a man who was treated for CMV retinitis and later developed IRU in the form of cystoid macular edema (CMO) even though his CMV retinitis remained inactive. His CMO resolved and visual acuity improved 2 years after the onset of CMO without any treatment interventions.Keywords: HIV, cystoid macular edema, AIDS, CMV retinitis Kathir YoganathanDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2010, Iss default, Pp 1065-1067 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Kathir Yoganathan Cystoid macular edema secondary to immune recovery uveitis in a man with cytomegalovirus retinitis and AIDS
description	Kathir YoganathanHIV/Genito-Urinary Medicine, Abertawe Bro Morgannwg University Health Board, Singleton hospital, Swansea, UKAbstract: Cytomegalovirus (CMV) is the most common intraocular opportunistic infection in profoundly immunocompromised patients with AIDS. It is characterized by an acute, progressive, necrotizing retinitis in patients with a CD4 count of &lt;50 cells/&micro;L. Although the incidence of CMV retinitis has declined because of the introduction of antiretroviral therapy (ART), a new syndrome of intraocular inflammation has emerged in patients with rising CD4 lymphocyte counts following ART. This is called immune recovery uveitis (IRU). It is thought to occur as a result of restored immunity to various infectious agents, commonly mycobacterial, Cryptococcus, and herpes virus infections. We report a man who was treated for CMV retinitis and later developed IRU in the form of cystoid macular edema (CMO) even though his CMV retinitis remained inactive. His CMO resolved and visual acuity improved 2 years after the onset of CMO without any treatment interventions.Keywords: HIV, cystoid macular edema, AIDS, CMV retinitis
format	article
author	Kathir Yoganathan
author_facet	Kathir Yoganathan
author_sort	Kathir Yoganathan
title	Cystoid macular edema secondary to immune recovery uveitis in a man with cytomegalovirus retinitis and AIDS
title_short	Cystoid macular edema secondary to immune recovery uveitis in a man with cytomegalovirus retinitis and AIDS
title_full	Cystoid macular edema secondary to immune recovery uveitis in a man with cytomegalovirus retinitis and AIDS
title_fullStr	Cystoid macular edema secondary to immune recovery uveitis in a man with cytomegalovirus retinitis and AIDS
title_full_unstemmed	Cystoid macular edema secondary to immune recovery uveitis in a man with cytomegalovirus retinitis and AIDS
title_sort	cystoid macular edema secondary to immune recovery uveitis in a man with cytomegalovirus retinitis and aids
publisher	Dove Medical Press
publishDate	2010
url	https://doaj.org/article/532107dbae404180ab3450fcdb4a91c0
work_keys_str_mv	AT kathiryoganathan cystoidmacularedemasecondarytoimmunerecoveryuveitisinamanwithcytomegalovirusretinitisandaids
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Cystoid macular edema secondary to immune recovery uveitis in a man with cytomegalovirus retinitis and AIDS

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