Candidate human genetic polymorphisms and severe malaria in a Tanzanian population.
Human genetic background strongly influences susceptibility to malaria infection and progression to severe disease and death. Classical genetic studies identified haemoglobinopathies and erythrocyte-associated polymorphisms, as protective against severe disease. High throughput genotyping by mass sp...
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Autores principales: | Alphaxard Manjurano, Taane G Clark, Behzad Nadjm, George Mtove, Hannah Wangai, Nuno Sepulveda, Susana G Campino, Caroline Maxwell, Raimos Olomi, Kirk R Rockett, Anna Jeffreys, MalariaGen Consortium, Eleanor M Riley, Hugh Reyburn, Christopher Drakeley |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/53266a31cff4474f82c5d21744ba0347 |
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