Candidate human genetic polymorphisms and severe malaria in a Tanzanian population.

Candidate human genetic polymorphisms and severe malaria in a Tanzanian population.

Human genetic background strongly influences susceptibility to malaria infection and progression to severe disease and death. Classical genetic studies identified haemoglobinopathies and erythrocyte-associated polymorphisms, as protective against severe disease. High throughput genotyping by mass sp...

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Autores principales: Alphaxard Manjurano, Taane G Clark, Behzad Nadjm, George Mtove, Hannah Wangai, Nuno Sepulveda, Susana G Campino, Caroline Maxwell, Raimos Olomi, Kirk R Rockett, Anna Jeffreys, MalariaGen Consortium, Eleanor M Riley, Hugh Reyburn, Christopher Drakeley
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/53266a31cff4474f82c5d21744ba0347
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