Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants
In breast cancer, genome-wide associations studies (GWAS) have highlighted loci associated with disease risk. Here, the authors perform a meta-analysis of GWAS data from Asian populations, discovering 31 potential new risk loci, 10 of which are validated in an independent disease cohort.
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Nature Portfolio
2020
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oai:doaj.org-article:532b4d0876ab46de877da9effc1e588e2021-12-02T14:42:13ZIdentification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants10.1038/s41467-020-15046-w2041-1723https://doaj.org/article/532b4d0876ab46de877da9effc1e588e2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15046-whttps://doaj.org/toc/2041-1723In breast cancer, genome-wide associations studies (GWAS) have highlighted loci associated with disease risk. Here, the authors perform a meta-analysis of GWAS data from Asian populations, discovering 31 potential new risk loci, 10 of which are validated in an independent disease cohort.Xiang ShuJirong LongQiuyin CaiSun-Seog KweonJi-Yeob ChoiMichiaki KuboSue K. ParkManjeet K. BollaJoe DennisQin WangYaohua YangJiajun ShiXingyi GuoBingshan LiRan TaoKristan J. AronsonKelvin Y. K. ChanTsun L. ChanYu-Tang GaoMikael HartmanWeang Kee HoHidemi ItoMotoki IwasakiHiroji IwataEsther M. JohnYoshio KasugaUi Soon KhooMi-Kyung KimSun-Young KongAllison W. KurianAva KwongEun-Sook LeeJingmei LiArtitaya LophatananonSiew-Kee LowShivaani MariapunKoichi MatsudaKeitaro MatsuoKenneth MuirDong-Young NohBoyoung ParkMin-Ho ParkChen-Yang ShenMin-Ho ShinJohn J. SpinelliAtsushi TakahashiChiuchen TsengShoichiro TsuganeAnna H. WuYong-Bing XiangTaiki YamajiYing ZhengRoger L. MilneAlison M. DunningPaul D. P. PharoahMontserrat García-ClosasSoo-Hwang TeoXiao-ou ShuDaehee KangDouglas F. EastonJacques SimardWei ZhengNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020) |
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DOAJ |
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DOAJ |
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EN |
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Science Q |
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Science Q Xiang Shu Jirong Long Qiuyin Cai Sun-Seog Kweon Ji-Yeob Choi Michiaki Kubo Sue K. Park Manjeet K. Bolla Joe Dennis Qin Wang Yaohua Yang Jiajun Shi Xingyi Guo Bingshan Li Ran Tao Kristan J. Aronson Kelvin Y. K. Chan Tsun L. Chan Yu-Tang Gao Mikael Hartman Weang Kee Ho Hidemi Ito Motoki Iwasaki Hiroji Iwata Esther M. John Yoshio Kasuga Ui Soon Khoo Mi-Kyung Kim Sun-Young Kong Allison W. Kurian Ava Kwong Eun-Sook Lee Jingmei Li Artitaya Lophatananon Siew-Kee Low Shivaani Mariapun Koichi Matsuda Keitaro Matsuo Kenneth Muir Dong-Young Noh Boyoung Park Min-Ho Park Chen-Yang Shen Min-Ho Shin John J. Spinelli Atsushi Takahashi Chiuchen Tseng Shoichiro Tsugane Anna H. Wu Yong-Bing Xiang Taiki Yamaji Ying Zheng Roger L. Milne Alison M. Dunning Paul D. P. Pharoah Montserrat García-Closas Soo-Hwang Teo Xiao-ou Shu Daehee Kang Douglas F. Easton Jacques Simard Wei Zheng Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants |
| description |
In breast cancer, genome-wide associations studies (GWAS) have highlighted loci associated with disease risk. Here, the authors perform a meta-analysis of GWAS data from Asian populations, discovering 31 potential new risk loci, 10 of which are validated in an independent disease cohort. |
| format |
article |
| author |
Xiang Shu Jirong Long Qiuyin Cai Sun-Seog Kweon Ji-Yeob Choi Michiaki Kubo Sue K. Park Manjeet K. Bolla Joe Dennis Qin Wang Yaohua Yang Jiajun Shi Xingyi Guo Bingshan Li Ran Tao Kristan J. Aronson Kelvin Y. K. Chan Tsun L. Chan Yu-Tang Gao Mikael Hartman Weang Kee Ho Hidemi Ito Motoki Iwasaki Hiroji Iwata Esther M. John Yoshio Kasuga Ui Soon Khoo Mi-Kyung Kim Sun-Young Kong Allison W. Kurian Ava Kwong Eun-Sook Lee Jingmei Li Artitaya Lophatananon Siew-Kee Low Shivaani Mariapun Koichi Matsuda Keitaro Matsuo Kenneth Muir Dong-Young Noh Boyoung Park Min-Ho Park Chen-Yang Shen Min-Ho Shin John J. Spinelli Atsushi Takahashi Chiuchen Tseng Shoichiro Tsugane Anna H. Wu Yong-Bing Xiang Taiki Yamaji Ying Zheng Roger L. Milne Alison M. Dunning Paul D. P. Pharoah Montserrat García-Closas Soo-Hwang Teo Xiao-ou Shu Daehee Kang Douglas F. Easton Jacques Simard Wei Zheng |
| author_facet |
Xiang Shu Jirong Long Qiuyin Cai Sun-Seog Kweon Ji-Yeob Choi Michiaki Kubo Sue K. Park Manjeet K. Bolla Joe Dennis Qin Wang Yaohua Yang Jiajun Shi Xingyi Guo Bingshan Li Ran Tao Kristan J. Aronson Kelvin Y. K. Chan Tsun L. Chan Yu-Tang Gao Mikael Hartman Weang Kee Ho Hidemi Ito Motoki Iwasaki Hiroji Iwata Esther M. John Yoshio Kasuga Ui Soon Khoo Mi-Kyung Kim Sun-Young Kong Allison W. Kurian Ava Kwong Eun-Sook Lee Jingmei Li Artitaya Lophatananon Siew-Kee Low Shivaani Mariapun Koichi Matsuda Keitaro Matsuo Kenneth Muir Dong-Young Noh Boyoung Park Min-Ho Park Chen-Yang Shen Min-Ho Shin John J. Spinelli Atsushi Takahashi Chiuchen Tseng Shoichiro Tsugane Anna H. Wu Yong-Bing Xiang Taiki Yamaji Ying Zheng Roger L. Milne Alison M. Dunning Paul D. P. Pharoah Montserrat García-Closas Soo-Hwang Teo Xiao-ou Shu Daehee Kang Douglas F. Easton Jacques Simard Wei Zheng |
| author_sort |
Xiang Shu |
| title |
Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants |
| title_short |
Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants |
| title_full |
Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants |
| title_fullStr |
Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants |
| title_full_unstemmed |
Identification of novel breast cancer susceptibility loci in meta-analyses conducted among Asian and European descendants |
| title_sort |
identification of novel breast cancer susceptibility loci in meta-analyses conducted among asian and european descendants |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/532b4d0876ab46de877da9effc1e588e |
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