Autophagy controls centrosome number by degrading Cep63

The ubiquitin-proteasome system is thought to be the primary regulator of centrosome number. Here, Watanabe et al. show that selective autophagy also plays a role in regulating centrosome number via p62-dependent recruitment of centrosomal protein 63 to autophagosomes.

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Autores principales:	Yuichiro Watanabe, Shinya Honda, Akimitsu Konishi, Satoko Arakawa, Michiko Murohashi, Hirofumi Yamaguchi, Satoru Torii, Minoru Tanabe, Shinji Tanaka, Eiji Warabi, Shigeomi Shimizu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5341a51a245b471d83b304d31da11c39
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spelling	oai:doaj.org-article:5341a51a245b471d83b304d31da11c392021-12-02T17:32:53ZAutophagy controls centrosome number by degrading Cep6310.1038/ncomms135082041-1723https://doaj.org/article/5341a51a245b471d83b304d31da11c392016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13508https://doaj.org/toc/2041-1723The ubiquitin-proteasome system is thought to be the primary regulator of centrosome number. Here, Watanabe et al. show that selective autophagy also plays a role in regulating centrosome number via p62-dependent recruitment of centrosomal protein 63 to autophagosomes.Yuichiro WatanabeShinya HondaAkimitsu KonishiSatoko ArakawaMichiko MurohashiHirofumi YamaguchiSatoru ToriiMinoru TanabeShinji TanakaEiji WarabiShigeomi ShimizuNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuichiro Watanabe Shinya Honda Akimitsu Konishi Satoko Arakawa Michiko Murohashi Hirofumi Yamaguchi Satoru Torii Minoru Tanabe Shinji Tanaka Eiji Warabi Shigeomi Shimizu Autophagy controls centrosome number by degrading Cep63
description	The ubiquitin-proteasome system is thought to be the primary regulator of centrosome number. Here, Watanabe et al. show that selective autophagy also plays a role in regulating centrosome number via p62-dependent recruitment of centrosomal protein 63 to autophagosomes.
format	article
author	Yuichiro Watanabe Shinya Honda Akimitsu Konishi Satoko Arakawa Michiko Murohashi Hirofumi Yamaguchi Satoru Torii Minoru Tanabe Shinji Tanaka Eiji Warabi Shigeomi Shimizu
author_facet	Yuichiro Watanabe Shinya Honda Akimitsu Konishi Satoko Arakawa Michiko Murohashi Hirofumi Yamaguchi Satoru Torii Minoru Tanabe Shinji Tanaka Eiji Warabi Shigeomi Shimizu
author_sort	Yuichiro Watanabe
title	Autophagy controls centrosome number by degrading Cep63
title_short	Autophagy controls centrosome number by degrading Cep63
title_full	Autophagy controls centrosome number by degrading Cep63
title_fullStr	Autophagy controls centrosome number by degrading Cep63
title_full_unstemmed	Autophagy controls centrosome number by degrading Cep63
title_sort	autophagy controls centrosome number by degrading cep63
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/5341a51a245b471d83b304d31da11c39
work_keys_str_mv	AT yuichirowatanabe autophagycontrolscentrosomenumberbydegradingcep63 AT shinyahonda autophagycontrolscentrosomenumberbydegradingcep63 AT akimitsukonishi autophagycontrolscentrosomenumberbydegradingcep63 AT satokoarakawa autophagycontrolscentrosomenumberbydegradingcep63 AT michikomurohashi autophagycontrolscentrosomenumberbydegradingcep63 AT hirofumiyamaguchi autophagycontrolscentrosomenumberbydegradingcep63 AT satorutorii autophagycontrolscentrosomenumberbydegradingcep63 AT minorutanabe autophagycontrolscentrosomenumberbydegradingcep63 AT shinjitanaka autophagycontrolscentrosomenumberbydegradingcep63 AT eijiwarabi autophagycontrolscentrosomenumberbydegradingcep63 AT shigeomishimizu autophagycontrolscentrosomenumberbydegradingcep63
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Autophagy controls centrosome number by degrading Cep63

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