Dendritic cell-elicited B-cell activation fosters immune privilege via IL-10 signals in hepatocellular carcinoma

Activation and biological function of B cells in cancer are still unclear. Here, the authors show that hepatocarcinoma cells drive the formation of semimature dendritic cells that in turn activate FcγRIIlow/−tumour B cells through the CD95L/CD95 axis, leading to the production of IL-10 and suppressi...

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Auteurs principaux: Fang-Zhu Ouyang, Rui-Qi Wu, Yuan Wei, Rui-Xian Liu, Dong Yang, Xiao Xiao, Limin Zheng, Bo Li, Xiang-Ming Lao, Dong-Ming Kuang
Format: article
Langue:EN
Publié: Nature Portfolio 2016
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Accès en ligne:https://doaj.org/article/534343b5bfdd47d7a44baf086ba66fd1
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