Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth

Preterm birth (PTB) has high prevalence and PTB infants have greater risk for mortality. Here, Hong and colleagues perform a genome-wide gene × environment interaction analysis and find that maternalCOL24A1variants have a significant interaction with maternal pre-pregnancy obesity in increasing PTB...

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Autores principales:	Xiumei Hong, Ke Hao, Hongkai Ji, Shouneng Peng, Ben Sherwood, Antonio Di Narzo, Hui-Ju Tsai, Xin Liu, Irina Burd, Guoying Wang, Yuelong Ji, Deanna Caruso, Guangyun Mao, Tami R. Bartell, Zhongyang Zhang, Colleen Pearson, Linda Heffner, Sandra Cerda, Terri H. Beaty, M. Daniele Fallin, Aviva Lee-Parritz, Barry Zuckerman, Daniel E. Weeks, Xiaobin Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/534b38ab0ad64986b9de0c06508d5eb6
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spelling	oai:doaj.org-article:534b38ab0ad64986b9de0c06508d5eb62021-12-02T15:39:05ZGenome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth10.1038/ncomms156082041-1723https://doaj.org/article/534b38ab0ad64986b9de0c06508d5eb62017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15608https://doaj.org/toc/2041-1723Preterm birth (PTB) has high prevalence and PTB infants have greater risk for mortality. Here, Hong and colleagues perform a genome-wide gene × environment interaction analysis and find that maternalCOL24A1variants have a significant interaction with maternal pre-pregnancy obesity in increasing PTB risk.Xiumei HongKe HaoHongkai JiShouneng PengBen SherwoodAntonio Di NarzoHui-Ju TsaiXin LiuIrina BurdGuoying WangYuelong JiDeanna CarusoGuangyun MaoTami R. BartellZhongyang ZhangColleen PearsonLinda HeffnerSandra CerdaTerri H. BeatyM. Daniele FallinAviva Lee-ParritzBarry ZuckermanDaniel E. WeeksXiaobin WangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiumei Hong Ke Hao Hongkai Ji Shouneng Peng Ben Sherwood Antonio Di Narzo Hui-Ju Tsai Xin Liu Irina Burd Guoying Wang Yuelong Ji Deanna Caruso Guangyun Mao Tami R. Bartell Zhongyang Zhang Colleen Pearson Linda Heffner Sandra Cerda Terri H. Beaty M. Daniele Fallin Aviva Lee-Parritz Barry Zuckerman Daniel E. Weeks Xiaobin Wang Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth
description	Preterm birth (PTB) has high prevalence and PTB infants have greater risk for mortality. Here, Hong and colleagues perform a genome-wide gene × environment interaction analysis and find that maternalCOL24A1variants have a significant interaction with maternal pre-pregnancy obesity in increasing PTB risk.
format	article
author	Xiumei Hong Ke Hao Hongkai Ji Shouneng Peng Ben Sherwood Antonio Di Narzo Hui-Ju Tsai Xin Liu Irina Burd Guoying Wang Yuelong Ji Deanna Caruso Guangyun Mao Tami R. Bartell Zhongyang Zhang Colleen Pearson Linda Heffner Sandra Cerda Terri H. Beaty M. Daniele Fallin Aviva Lee-Parritz Barry Zuckerman Daniel E. Weeks Xiaobin Wang
author_facet	Xiumei Hong Ke Hao Hongkai Ji Shouneng Peng Ben Sherwood Antonio Di Narzo Hui-Ju Tsai Xin Liu Irina Burd Guoying Wang Yuelong Ji Deanna Caruso Guangyun Mao Tami R. Bartell Zhongyang Zhang Colleen Pearson Linda Heffner Sandra Cerda Terri H. Beaty M. Daniele Fallin Aviva Lee-Parritz Barry Zuckerman Daniel E. Weeks Xiaobin Wang
author_sort	Xiumei Hong
title	Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth
title_short	Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth
title_full	Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth
title_fullStr	Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth
title_full_unstemmed	Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth
title_sort	genome-wide approach identifies a novel gene-maternal pre-pregnancy bmi interaction on preterm birth
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/534b38ab0ad64986b9de0c06508d5eb6
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Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth

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