HIF-1 and c-Src mediate increased glucose uptake induced by endothelin-1 and connexin43 in astrocytes.
In previous work we showed that endothelin-1 (ET-1) increases the rate of glucose uptake in astrocytes, an important aspect of brain function since glucose taken up by astrocytes is used to supply the neurons with metabolic substrates. In the present work we sought to identify the signalling pathway...
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Autores principales: | José Carlos Valle-Casuso, Ana González-Sánchez, José M Medina, Arantxa Tabernero |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Acceso en línea: | https://doaj.org/article/534c50bb1b8843618581c27ea5755c5e |
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