Multi-scale imaging and analysis identify pan-embryo cell dynamics of germlayer formation in zebrafish

The precise cell dynamics of early development have not yet been visualized. Here, the authors use custom 4-lens light sheet microscopy to image and analyze the dynamics of all three fluorescently labeled germlayers, yielding a comprehensive, pan-embryo description of early zebrafish gastrulation.

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Detalles Bibliográficos
Autores principales: Gopi Shah, Konstantin Thierbach, Benjamin Schmid, Johannes Waschke, Anna Reade, Mario Hlawitschka, Ingo Roeder, Nico Scherf, Jan Huisken
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/534f9ca0e5a045ae874388bed39dd3e3
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Descripción
Sumario:The precise cell dynamics of early development have not yet been visualized. Here, the authors use custom 4-lens light sheet microscopy to image and analyze the dynamics of all three fluorescently labeled germlayers, yielding a comprehensive, pan-embryo description of early zebrafish gastrulation.