A neural basis for antagonistic control of feeding and compulsive behaviors

Feeding disorders are often comorbid with compulsive behaviours but the underlying neural circuits are not known. Here the authors demonstrate that glutamatergic and GABAergic projections from the LH to the PVH exert antagonistic effects on grooming and feeding via modulation of PVH neuron activity.

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Autores principales:	Leandra R. Mangieri, Yungang Lu, Yuanzhong Xu, Ryan M. Cassidy, Yong Xu, Benjamin R. Arenkiel, Qingchun Tong
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/53541804e2c140519745f50b0fe25934
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spelling	oai:doaj.org-article:53541804e2c140519745f50b0fe259342021-12-02T16:49:35ZA neural basis for antagonistic control of feeding and compulsive behaviors10.1038/s41467-017-02534-92041-1723https://doaj.org/article/53541804e2c140519745f50b0fe259342018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02534-9https://doaj.org/toc/2041-1723Feeding disorders are often comorbid with compulsive behaviours but the underlying neural circuits are not known. Here the authors demonstrate that glutamatergic and GABAergic projections from the LH to the PVH exert antagonistic effects on grooming and feeding via modulation of PVH neuron activity.Leandra R. MangieriYungang LuYuanzhong XuRyan M. CassidyYong XuBenjamin R. ArenkielQingchun TongNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Leandra R. Mangieri Yungang Lu Yuanzhong Xu Ryan M. Cassidy Yong Xu Benjamin R. Arenkiel Qingchun Tong A neural basis for antagonistic control of feeding and compulsive behaviors
description	Feeding disorders are often comorbid with compulsive behaviours but the underlying neural circuits are not known. Here the authors demonstrate that glutamatergic and GABAergic projections from the LH to the PVH exert antagonistic effects on grooming and feeding via modulation of PVH neuron activity.
format	article
author	Leandra R. Mangieri Yungang Lu Yuanzhong Xu Ryan M. Cassidy Yong Xu Benjamin R. Arenkiel Qingchun Tong
author_facet	Leandra R. Mangieri Yungang Lu Yuanzhong Xu Ryan M. Cassidy Yong Xu Benjamin R. Arenkiel Qingchun Tong
author_sort	Leandra R. Mangieri
title	A neural basis for antagonistic control of feeding and compulsive behaviors
title_short	A neural basis for antagonistic control of feeding and compulsive behaviors
title_full	A neural basis for antagonistic control of feeding and compulsive behaviors
title_fullStr	A neural basis for antagonistic control of feeding and compulsive behaviors
title_full_unstemmed	A neural basis for antagonistic control of feeding and compulsive behaviors
title_sort	neural basis for antagonistic control of feeding and compulsive behaviors
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/53541804e2c140519745f50b0fe25934
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A neural basis for antagonistic control of feeding and compulsive behaviors

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