A neural basis for antagonistic control of feeding and compulsive behaviors

Feeding disorders are often comorbid with compulsive behaviours but the underlying neural circuits are not known. Here the authors demonstrate that glutamatergic and GABAergic projections from the LH to the PVH exert antagonistic effects on grooming and feeding via modulation of PVH neuron activity.

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Bibliographic Details
Main Authors: Leandra R. Mangieri, Yungang Lu, Yuanzhong Xu, Ryan M. Cassidy, Yong Xu, Benjamin R. Arenkiel, Qingchun Tong
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/53541804e2c140519745f50b0fe25934
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