Targeting Oxidative Stress: Novel Coumarin-Based Inverse Agonists of GPR55

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Targeting Oxidative Stress: Novel Coumarin-Based Inverse Agonists of GPR55

Oxidative stress is associated with different neurological and psychiatric diseases. Therefore, development of new pharmaceuticals targeting oxidative dysregulation might be a promising approach to treat these diseases. The G-protein coupled receptor 55 (GPR55) is broadly expressed in central nervou...

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Autores principales:	Matthias Apweiler, Soraya Wilke Saliba, Jana Streyczek, Thomas Hurrle, Simone Gräßle, Stefan Bräse, Bernd L. Fiebich
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	oxidative stress GPR55 coumarin-based compounds ROS inverse agonism 8-Iso-PGF<sub>2α</sub> Biology (General) QH301-705.5 Chemistry QD1-999
Acceso en línea:	https://doaj.org/article/53573912c7d940c28090b1526114831b
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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