A compartment model of VEGF distribution in humans in the presence of soluble VEGF receptor-1 acting as a ligand trap.
Vascular endothelial growth factor (VEGF), through its activation of cell surface receptor tyrosine kinases including VEGFR1 and VEGFR2, is a vital regulator of stimulatory and inhibitory processes that keep angiogenesis--new capillary growth from existing microvasculature--at a dynamic balance in n...
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Autores principales: | Florence T H Wu, Marianne O Stefanini, Feilim Mac Gabhann, Aleksander S Popel |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2009
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Materias: | |
Acceso en línea: | https://doaj.org/article/535c8d177efe416582c1171d841a00ae |
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