Landfill Leachate from an Urban Solid Waste Storage System Produces Genotoxicity and Cytotoxicity in Pre-Adolescent and Young Adults Rats

Landfill leachate is a complex mixture of organic and inorganic molecules, as well as environmental pollutants that can cause harm to ecosystems and living beings. The micronucleus test in peripheral blood erythrocytes was used to evaluate the genotoxic and cytotoxic effects of exposure to a landfil...

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Autores principales:	Omar Ricardo Torres-González, Ivan Moisés Sánchez-Hernández, Mario Eduardo Flores-Soto, Verónica Chaparro-Huerta, Cesar Soria-Fregozo, Laura Hernández-García, Eduardo Padilla-Camberos, José Miguel Flores-Fernández
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	leachate urban solid waste storage system genotoxicity cytotoxicity Medicine R
Acceso en línea:	https://doaj.org/article/538cb78c6ba44a48b866b30f396f5cd4
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spelling	oai:doaj.org-article:538cb78c6ba44a48b866b30f396f5cd42021-11-11T16:11:25ZLandfill Leachate from an Urban Solid Waste Storage System Produces Genotoxicity and Cytotoxicity in Pre-Adolescent and Young Adults Rats10.3390/ijerph1821110291660-46011661-7827https://doaj.org/article/538cb78c6ba44a48b866b30f396f5cd42021-10-01T00:00:00Zhttps://www.mdpi.com/1660-4601/18/21/11029https://doaj.org/toc/1661-7827https://doaj.org/toc/1660-4601Landfill leachate is a complex mixture of organic and inorganic molecules, as well as environmental pollutants that can cause harm to ecosystems and living beings. The micronucleus test in peripheral blood erythrocytes was used to evaluate the genotoxic and cytotoxic effects of exposure to a landfill leachate from an outdoor solid waste storage system on Wistar strain rats at different developmental stages, pre-adolescents and young adults, and the heavy metal content of the leachate was determined by atomic absorption spectrometry. Contents of arsenic, cadmium, chromium, mercury, and lead in the landfill leachate were outside the allowable international standards, and the exposure to the landfill leachate caused genotoxic and cytotoxic effects on Wistar rats, where the pre-adolescent animals were more susceptible to the toxics contained in the landfill leachate than young adults. Heavy metals contained in landfill leachate, individually or synergically with other molecules can be responsible for clastogenic and cytotoxic effects that can be harmful to humans and ecosystems.Omar Ricardo Torres-GonzálezIvan Moisés Sánchez-HernándezMario Eduardo Flores-SotoVerónica Chaparro-HuertaCesar Soria-FregozoLaura Hernández-GarcíaEduardo Padilla-CamberosJosé Miguel Flores-FernándezMDPI AGarticleleachateurban solid waste storage systemgenotoxicitycytotoxicityMedicineRENInternational Journal of Environmental Research and Public Health, Vol 18, Iss 11029, p 11029 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	leachate urban solid waste storage system genotoxicity cytotoxicity Medicine R
spellingShingle	leachate urban solid waste storage system genotoxicity cytotoxicity Medicine R Omar Ricardo Torres-González Ivan Moisés Sánchez-Hernández Mario Eduardo Flores-Soto Verónica Chaparro-Huerta Cesar Soria-Fregozo Laura Hernández-García Eduardo Padilla-Camberos José Miguel Flores-Fernández Landfill Leachate from an Urban Solid Waste Storage System Produces Genotoxicity and Cytotoxicity in Pre-Adolescent and Young Adults Rats
description	Landfill leachate is a complex mixture of organic and inorganic molecules, as well as environmental pollutants that can cause harm to ecosystems and living beings. The micronucleus test in peripheral blood erythrocytes was used to evaluate the genotoxic and cytotoxic effects of exposure to a landfill leachate from an outdoor solid waste storage system on Wistar strain rats at different developmental stages, pre-adolescents and young adults, and the heavy metal content of the leachate was determined by atomic absorption spectrometry. Contents of arsenic, cadmium, chromium, mercury, and lead in the landfill leachate were outside the allowable international standards, and the exposure to the landfill leachate caused genotoxic and cytotoxic effects on Wistar rats, where the pre-adolescent animals were more susceptible to the toxics contained in the landfill leachate than young adults. Heavy metals contained in landfill leachate, individually or synergically with other molecules can be responsible for clastogenic and cytotoxic effects that can be harmful to humans and ecosystems.
format	article
author	Omar Ricardo Torres-González Ivan Moisés Sánchez-Hernández Mario Eduardo Flores-Soto Verónica Chaparro-Huerta Cesar Soria-Fregozo Laura Hernández-García Eduardo Padilla-Camberos José Miguel Flores-Fernández
author_facet	Omar Ricardo Torres-González Ivan Moisés Sánchez-Hernández Mario Eduardo Flores-Soto Verónica Chaparro-Huerta Cesar Soria-Fregozo Laura Hernández-García Eduardo Padilla-Camberos José Miguel Flores-Fernández
author_sort	Omar Ricardo Torres-González
title	Landfill Leachate from an Urban Solid Waste Storage System Produces Genotoxicity and Cytotoxicity in Pre-Adolescent and Young Adults Rats
title_short	Landfill Leachate from an Urban Solid Waste Storage System Produces Genotoxicity and Cytotoxicity in Pre-Adolescent and Young Adults Rats
title_full	Landfill Leachate from an Urban Solid Waste Storage System Produces Genotoxicity and Cytotoxicity in Pre-Adolescent and Young Adults Rats
title_fullStr	Landfill Leachate from an Urban Solid Waste Storage System Produces Genotoxicity and Cytotoxicity in Pre-Adolescent and Young Adults Rats
title_full_unstemmed	Landfill Leachate from an Urban Solid Waste Storage System Produces Genotoxicity and Cytotoxicity in Pre-Adolescent and Young Adults Rats
title_sort	landfill leachate from an urban solid waste storage system produces genotoxicity and cytotoxicity in pre-adolescent and young adults rats
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/538cb78c6ba44a48b866b30f396f5cd4
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Landfill Leachate from an Urban Solid Waste Storage System Produces Genotoxicity and Cytotoxicity in Pre-Adolescent and Young Adults Rats

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