A case report describing the immune response of an infant with congenital heart disease and severe COVID-19
Wurzel et al. describe the kinetics of the immune response in relation to clinical and virological features in a 5-month old infant with congenital heart disease and severe COVID-19. The immune response was characterised by an elevated inflammatory response in the acute phase of infection, followed...
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Nature Portfolio
2021
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oai:doaj.org-article:539146c00b4f4971b5652d9fc162ec202021-11-21T12:15:57ZA case report describing the immune response of an infant with congenital heart disease and severe COVID-1910.1038/s43856-021-00047-72730-664Xhttps://doaj.org/article/539146c00b4f4971b5652d9fc162ec202021-11-01T00:00:00Zhttps://doi.org/10.1038/s43856-021-00047-7https://doaj.org/toc/2730-664XWurzel et al. describe the kinetics of the immune response in relation to clinical and virological features in a 5-month old infant with congenital heart disease and severe COVID-19. The immune response was characterised by an elevated inflammatory response in the acute phase of infection, followed by Th2 skewing and prolonged T cell activation.Danielle WurzelMelanie R. NeelandJeremy AndersonYara-Natalie AboLien Anh Ha DoCeleste M. DonatoJulie E. BinesZheng Quan TohRachel A. HigginsSedi JalaliTheresa ColeKanta SubbaraoAlissa McMinnKate DohleGabrielle M. HaeuslerSarah McNabAnnette AlafaciIsabella OvermarsVanessa CliffordLai-yang LeeAndrew J. DaleyJim ButteryPenelope A. BryantDavid BurgnerAndrew SteerShidan TosifIgor E. KonstantinovTrevor DukePaul V. LicciardiDaniel G. PellicciNigel W. CrawfordNature PortfolioarticleMedicineRENCommunications Medicine, Vol 1, Iss 1, Pp 1-7 (2021) |
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DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Medicine R |
| spellingShingle |
Medicine R Danielle Wurzel Melanie R. Neeland Jeremy Anderson Yara-Natalie Abo Lien Anh Ha Do Celeste M. Donato Julie E. Bines Zheng Quan Toh Rachel A. Higgins Sedi Jalali Theresa Cole Kanta Subbarao Alissa McMinn Kate Dohle Gabrielle M. Haeusler Sarah McNab Annette Alafaci Isabella Overmars Vanessa Clifford Lai-yang Lee Andrew J. Daley Jim Buttery Penelope A. Bryant David Burgner Andrew Steer Shidan Tosif Igor E. Konstantinov Trevor Duke Paul V. Licciardi Daniel G. Pellicci Nigel W. Crawford A case report describing the immune response of an infant with congenital heart disease and severe COVID-19 |
| description |
Wurzel et al. describe the kinetics of the immune response in relation to clinical and virological features in a 5-month old infant with congenital heart disease and severe COVID-19. The immune response was characterised by an elevated inflammatory response in the acute phase of infection, followed by Th2 skewing and prolonged T cell activation. |
| format |
article |
| author |
Danielle Wurzel Melanie R. Neeland Jeremy Anderson Yara-Natalie Abo Lien Anh Ha Do Celeste M. Donato Julie E. Bines Zheng Quan Toh Rachel A. Higgins Sedi Jalali Theresa Cole Kanta Subbarao Alissa McMinn Kate Dohle Gabrielle M. Haeusler Sarah McNab Annette Alafaci Isabella Overmars Vanessa Clifford Lai-yang Lee Andrew J. Daley Jim Buttery Penelope A. Bryant David Burgner Andrew Steer Shidan Tosif Igor E. Konstantinov Trevor Duke Paul V. Licciardi Daniel G. Pellicci Nigel W. Crawford |
| author_facet |
Danielle Wurzel Melanie R. Neeland Jeremy Anderson Yara-Natalie Abo Lien Anh Ha Do Celeste M. Donato Julie E. Bines Zheng Quan Toh Rachel A. Higgins Sedi Jalali Theresa Cole Kanta Subbarao Alissa McMinn Kate Dohle Gabrielle M. Haeusler Sarah McNab Annette Alafaci Isabella Overmars Vanessa Clifford Lai-yang Lee Andrew J. Daley Jim Buttery Penelope A. Bryant David Burgner Andrew Steer Shidan Tosif Igor E. Konstantinov Trevor Duke Paul V. Licciardi Daniel G. Pellicci Nigel W. Crawford |
| author_sort |
Danielle Wurzel |
| title |
A case report describing the immune response of an infant with congenital heart disease and severe COVID-19 |
| title_short |
A case report describing the immune response of an infant with congenital heart disease and severe COVID-19 |
| title_full |
A case report describing the immune response of an infant with congenital heart disease and severe COVID-19 |
| title_fullStr |
A case report describing the immune response of an infant with congenital heart disease and severe COVID-19 |
| title_full_unstemmed |
A case report describing the immune response of an infant with congenital heart disease and severe COVID-19 |
| title_sort |
case report describing the immune response of an infant with congenital heart disease and severe covid-19 |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/539146c00b4f4971b5652d9fc162ec20 |
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