Attenuation of Live-Attenuated Yellow Fever 17D Vaccine Virus Is Localized to a High-Fidelity Replication Complex
ABSTRACT The molecular basis of attenuation for live-attenuated vaccines is poorly understood. The yellow fever (YF) 17D vaccine virus was derived from the wild-type, parental strain Asibi virus by serial passage in chicken tissue and has proven to be a very safe and efficacious vaccine. We have pre...
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Autores principales: | Emily H. Davis, Andrew S. Beck, Ashley E. Strother, Jill K. Thompson, Steven G. Widen, Stephen Higgs, Thomas G. Wood, Alan D. T. Barrett |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/53976fd2f87345f895f1d65a2bf155c0 |
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