Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses

MnO2 nanostructures are promising TME-responsive theranostic agents in cancer. Here, the authors develop a nano-platform based on hollow H-MnO2 nanoshells able to modulate the tissue microenvironment, release a drug and inhibit tumor growth alone or in combination with check-point blockade therapy.

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Autores principales:	Guangbao Yang, Ligeng Xu, Yu Chao, Jun Xu, Xiaoqi Sun, Yifan Wu, Rui Peng, Zhuang Liu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/53987783f714404fab624f966787efee
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spelling	oai:doaj.org-article:53987783f714404fab624f966787efee2021-12-02T14:42:41ZHollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses10.1038/s41467-017-01050-02041-1723https://doaj.org/article/53987783f714404fab624f966787efee2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01050-0https://doaj.org/toc/2041-1723MnO2 nanostructures are promising TME-responsive theranostic agents in cancer. Here, the authors develop a nano-platform based on hollow H-MnO2 nanoshells able to modulate the tissue microenvironment, release a drug and inhibit tumor growth alone or in combination with check-point blockade therapy.Guangbao YangLigeng XuYu ChaoJun XuXiaoqi SunYifan WuRui PengZhuang LiuNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Guangbao Yang Ligeng Xu Yu Chao Jun Xu Xiaoqi Sun Yifan Wu Rui Peng Zhuang Liu Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses
description	MnO2 nanostructures are promising TME-responsive theranostic agents in cancer. Here, the authors develop a nano-platform based on hollow H-MnO2 nanoshells able to modulate the tissue microenvironment, release a drug and inhibit tumor growth alone or in combination with check-point blockade therapy.
format	article
author	Guangbao Yang Ligeng Xu Yu Chao Jun Xu Xiaoqi Sun Yifan Wu Rui Peng Zhuang Liu
author_facet	Guangbao Yang Ligeng Xu Yu Chao Jun Xu Xiaoqi Sun Yifan Wu Rui Peng Zhuang Liu
author_sort	Guangbao Yang
title	Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses
title_short	Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses
title_full	Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses
title_fullStr	Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses
title_full_unstemmed	Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses
title_sort	hollow mno2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/53987783f714404fab624f966787efee
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Hollow MnO2 as a tumor-microenvironment-responsive biodegradable nano-platform for combination therapy favoring antitumor immune responses

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