Genetics of PICALM expression and Alzheimer's disease.

Novel Alzheimer's disease (AD) risk factors have been identified by genome-wide association studies. Elucidating the mechanism underlying these factors is critical to the validation process and, by identifying rate-limiting steps in AD risk, may yield novel therapeutic targets. Here, we evaluat...

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Autores principales: Ishita Parikh, David W Fardo, Steven Estus
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/539952d6005c419a81a4841fa17cbc73
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