Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males

The mammalian SWI/SNF nucleosome remodeler is required for spermatogenesis. Here, the authors show that PBAF is essential for meiotic cell division in males and required to activate the expression of critical genes involved in spindle assembly and nuclear division in spermatocytes.

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Auteurs principaux:	Debashish U. Menon, Oleksandr Kirsanov, Christopher B. Geyer, Terry Magnuson
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/53abd842e43d42eaa5ed98e2367f7dbe
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id	oai:doaj.org-article:53abd842e43d42eaa5ed98e2367f7dbe
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spelling	oai:doaj.org-article:53abd842e43d42eaa5ed98e2367f7dbe2021-11-14T12:35:40ZMammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males10.1038/s41467-021-26828-12041-1723https://doaj.org/article/53abd842e43d42eaa5ed98e2367f7dbe2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26828-1https://doaj.org/toc/2041-1723The mammalian SWI/SNF nucleosome remodeler is required for spermatogenesis. Here, the authors show that PBAF is essential for meiotic cell division in males and required to activate the expression of critical genes involved in spindle assembly and nuclear division in spermatocytes.Debashish U. MenonOleksandr KirsanovChristopher B. GeyerTerry MagnusonNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Debashish U. Menon Oleksandr Kirsanov Christopher B. Geyer Terry Magnuson Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males
description	The mammalian SWI/SNF nucleosome remodeler is required for spermatogenesis. Here, the authors show that PBAF is essential for meiotic cell division in males and required to activate the expression of critical genes involved in spindle assembly and nuclear division in spermatocytes.
format	article
author	Debashish U. Menon Oleksandr Kirsanov Christopher B. Geyer Terry Magnuson
author_facet	Debashish U. Menon Oleksandr Kirsanov Christopher B. Geyer Terry Magnuson
author_sort	Debashish U. Menon
title	Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males
title_short	Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males
title_full	Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males
title_fullStr	Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males
title_full_unstemmed	Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males
title_sort	mammalian swi/snf chromatin remodeler is essential for reductional meiosis in males
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/53abd842e43d42eaa5ed98e2367f7dbe
work_keys_str_mv	AT debashishumenon mammalianswisnfchromatinremodelerisessentialforreductionalmeiosisinmales AT oleksandrkirsanov mammalianswisnfchromatinremodelerisessentialforreductionalmeiosisinmales AT christopherbgeyer mammalianswisnfchromatinremodelerisessentialforreductionalmeiosisinmales AT terrymagnuson mammalianswisnfchromatinremodelerisessentialforreductionalmeiosisinmales
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Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males

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