Heterogeneous recruitment abilities to RNA polymerases generate nonlinear scaling of gene expression with cell volume

Expression levels of most genes are proportional to cell volumes, although some genes exhibit nonlinear scaling of expression levels with cell volume. Here the authors provide a model that reveals nonlinear scaling is a direct consequence of heterogeneous recruitment abilities of promoters to RNA po...

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Auteurs principaux: Qirun Wang, Jie Lin
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Q
Accès en ligne:https://doaj.org/article/53b1ccbbbf18473abbb782fb64bd2c74
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