Bilateral presumed astrocytic hamartomas in a patient with retinitis pigmentosa

Michael Kinori1, Iris Moroz1,2, Ygal Rotenstreich1,2, Hagith Yonath2,3, Ido Didi Fabian1, Vicktoria Vishnevskia-Dai1,21Department of Ophthalmology, Chaim Sheba Medical Center, Tel Hashomer, Israel; 2Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; 3Danek Gertner Genetic Institute...

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Autores principales:	Kinori M, Moroz I, Rotenstreich Y, Yonath H, Fabian ID, Vishnevskia-Dai V
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2011
Materias:	Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/53b46422fdc94bda841502ff4fc57538
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spelling	oai:doaj.org-article:53b46422fdc94bda841502ff4fc575382021-12-02T03:11:02ZBilateral presumed astrocytic hamartomas in a patient with retinitis pigmentosa1177-54671177-5483https://doaj.org/article/53b46422fdc94bda841502ff4fc575382011-11-01T00:00:00Zhttp://www.dovepress.com/bilateral-presumed-astrocytic-hamartomas-in-a-patient-with-retinitis-p-a8727https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Michael Kinori1, Iris Moroz1,2, Ygal Rotenstreich1,2, Hagith Yonath2,3, Ido Didi Fabian1, Vicktoria Vishnevskia-Dai1,21Department of Ophthalmology, Chaim Sheba Medical Center, Tel Hashomer, Israel; 2Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; 3Danek Gertner Genetic Institute and Internal Medicine A, Chaim Sheba Medical Center, Tel Hashomer, IsraelAbstract: Retinal astrocytic hamartomas are benign intraocular tumors classically associated with phacomatoses. Their appearance in isolation is rare. An association between astrocytic hamartomas and retinitis pigmentosa (RP) has been described previously, but controversy still exists regarding the precise nature of these lesions in RP patients. The authors present a case report of a 24-year-old male with RP and multiple bilateral lesions clinically consistent with retinal astrocytic hamartomas. Optical coherence tomography revealed multiple bilateral hyper-reflective intraretinal masses, loss of retinal architecture, intralesional calcifications, and prominent optical posterior shadowing. Comprehensive systemic evaluation was negative for phacomatoses. However, given that a biopsy was not performed, the diagnosis of optic nerve head drusen could not be excluded.Keywords: giant drusen, optic nerve head drusen, optical coherence tomography, intraocular tumorKinori MMoroz IRotenstreich YYonath HFabian IDVishnevskia-Dai VDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2011, Iss default, Pp 1663-1665 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Ophthalmology RE1-994
spellingShingle	Ophthalmology RE1-994 Kinori M Moroz I Rotenstreich Y Yonath H Fabian ID Vishnevskia-Dai V Bilateral presumed astrocytic hamartomas in a patient with retinitis pigmentosa
description	Michael Kinori1, Iris Moroz1,2, Ygal Rotenstreich1,2, Hagith Yonath2,3, Ido Didi Fabian1, Vicktoria Vishnevskia-Dai1,21Department of Ophthalmology, Chaim Sheba Medical Center, Tel Hashomer, Israel; 2Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; 3Danek Gertner Genetic Institute and Internal Medicine A, Chaim Sheba Medical Center, Tel Hashomer, IsraelAbstract: Retinal astrocytic hamartomas are benign intraocular tumors classically associated with phacomatoses. Their appearance in isolation is rare. An association between astrocytic hamartomas and retinitis pigmentosa (RP) has been described previously, but controversy still exists regarding the precise nature of these lesions in RP patients. The authors present a case report of a 24-year-old male with RP and multiple bilateral lesions clinically consistent with retinal astrocytic hamartomas. Optical coherence tomography revealed multiple bilateral hyper-reflective intraretinal masses, loss of retinal architecture, intralesional calcifications, and prominent optical posterior shadowing. Comprehensive systemic evaluation was negative for phacomatoses. However, given that a biopsy was not performed, the diagnosis of optic nerve head drusen could not be excluded.Keywords: giant drusen, optic nerve head drusen, optical coherence tomography, intraocular tumor
format	article
author	Kinori M Moroz I Rotenstreich Y Yonath H Fabian ID Vishnevskia-Dai V
author_facet	Kinori M Moroz I Rotenstreich Y Yonath H Fabian ID Vishnevskia-Dai V
author_sort	Kinori M
title	Bilateral presumed astrocytic hamartomas in a patient with retinitis pigmentosa
title_short	Bilateral presumed astrocytic hamartomas in a patient with retinitis pigmentosa
title_full	Bilateral presumed astrocytic hamartomas in a patient with retinitis pigmentosa
title_fullStr	Bilateral presumed astrocytic hamartomas in a patient with retinitis pigmentosa
title_full_unstemmed	Bilateral presumed astrocytic hamartomas in a patient with retinitis pigmentosa
title_sort	bilateral presumed astrocytic hamartomas in a patient with retinitis pigmentosa
publisher	Dove Medical Press
publishDate	2011
url	https://doaj.org/article/53b46422fdc94bda841502ff4fc57538
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Bilateral presumed astrocytic hamartomas in a patient with retinitis pigmentosa

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