Size-selective molecular recognition based on a confined DNA molecular sieve using cavity-tunable framework nucleic acids

Size-selective discrimination is an issue in biosensing. Here, the authors report on a size selective DNA nanocage which excludes agents based on size and protects the probes against degradation, and demonstrate the discrimination between mature and precursor miRNA.

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Bibliographic Details
Main Authors: Xiaoyi Fu, Guoliang Ke, Fangqi Peng, Xue Hu, Jiaqi Li, Yuyan Shi, Gezhi Kong, Xiao-Bing Zhang, Weihong Tan
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/53ba307b54b744d5b77aee3194ec4a79
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Summary:Size-selective discrimination is an issue in biosensing. Here, the authors report on a size selective DNA nanocage which excludes agents based on size and protects the probes against degradation, and demonstrate the discrimination between mature and precursor miRNA.