Size-selective molecular recognition based on a confined DNA molecular sieve using cavity-tunable framework nucleic acids

Size-selective discrimination is an issue in biosensing. Here, the authors report on a size selective DNA nanocage which excludes agents based on size and protects the probes against degradation, and demonstrate the discrimination between mature and precursor miRNA.

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Autores principales: Xiaoyi Fu, Guoliang Ke, Fangqi Peng, Xue Hu, Jiaqi Li, Yuyan Shi, Gezhi Kong, Xiao-Bing Zhang, Weihong Tan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/53ba307b54b744d5b77aee3194ec4a79
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spelling oai:doaj.org-article:53ba307b54b744d5b77aee3194ec4a792021-12-02T16:49:15ZSize-selective molecular recognition based on a confined DNA molecular sieve using cavity-tunable framework nucleic acids10.1038/s41467-020-15297-72041-1723https://doaj.org/article/53ba307b54b744d5b77aee3194ec4a792020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15297-7https://doaj.org/toc/2041-1723Size-selective discrimination is an issue in biosensing. Here, the authors report on a size selective DNA nanocage which excludes agents based on size and protects the probes against degradation, and demonstrate the discrimination between mature and precursor miRNA.Xiaoyi FuGuoliang KeFangqi PengXue HuJiaqi LiYuyan ShiGezhi KongXiao-Bing ZhangWeihong TanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Xiaoyi Fu
Guoliang Ke
Fangqi Peng
Xue Hu
Jiaqi Li
Yuyan Shi
Gezhi Kong
Xiao-Bing Zhang
Weihong Tan
Size-selective molecular recognition based on a confined DNA molecular sieve using cavity-tunable framework nucleic acids
description Size-selective discrimination is an issue in biosensing. Here, the authors report on a size selective DNA nanocage which excludes agents based on size and protects the probes against degradation, and demonstrate the discrimination between mature and precursor miRNA.
format article
author Xiaoyi Fu
Guoliang Ke
Fangqi Peng
Xue Hu
Jiaqi Li
Yuyan Shi
Gezhi Kong
Xiao-Bing Zhang
Weihong Tan
author_facet Xiaoyi Fu
Guoliang Ke
Fangqi Peng
Xue Hu
Jiaqi Li
Yuyan Shi
Gezhi Kong
Xiao-Bing Zhang
Weihong Tan
author_sort Xiaoyi Fu
title Size-selective molecular recognition based on a confined DNA molecular sieve using cavity-tunable framework nucleic acids
title_short Size-selective molecular recognition based on a confined DNA molecular sieve using cavity-tunable framework nucleic acids
title_full Size-selective molecular recognition based on a confined DNA molecular sieve using cavity-tunable framework nucleic acids
title_fullStr Size-selective molecular recognition based on a confined DNA molecular sieve using cavity-tunable framework nucleic acids
title_full_unstemmed Size-selective molecular recognition based on a confined DNA molecular sieve using cavity-tunable framework nucleic acids
title_sort size-selective molecular recognition based on a confined dna molecular sieve using cavity-tunable framework nucleic acids
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/53ba307b54b744d5b77aee3194ec4a79
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