Insights Into the Role of CSF1R in the Central Nervous System and Neurological Disorders

QR Code

Insights Into the Role of CSF1R in the Central Nervous System and Neurological Disorders

The colony-stimulating factor 1 receptor (CSF1R) is a key tyrosine kinase transmembrane receptor modulating microglial homeostasis, neurogenesis, and neuronal survival in the central nervous system (CNS). CSF1R, which can be proteolytically cleaved into a soluble ectodomain and an intracellular prot...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Banglian Hu, Shengshun Duan, Ziwei Wang, Xin Li, Yuhang Zhou, Xian Zhang, Yun-Wu Zhang, Huaxi Xu, Honghua Zheng
Format:	article
Langue:	EN
Publié:	Frontiers Media S.A. 2021
Sujets:	CSF1R microglia microglial maintenance neurogenesis CSF1R cleavage CSF1R mutations Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Accès en ligne:	https://doaj.org/article/53bb5fb9cc324956904e32d33c9434ab
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires

CSF1R Inhibition Combined with GM-CSF Reprograms Macrophages and Disrupts Protumoral Interplays with AML Cells
par: Tatiana Smirnova, et autres
Publié: (2021)

T Cell Production of GM-CSF Protects the Host during Experimental Tuberculosis
par: Richard T. Robinson
Publié: (2017)

Immunohistochemical Identification of GM-CSF in Testis of Rats with Oligozoospermia with the Intervention of Cuscuta chinensis Flavonoids
par: Xiaotong,Meng, et autres
Publié: (2020)

Treatment With the CSF1R Antagonist GW2580, Sensitizes Microglia to Reactive Oxygen Species
par: Katiria Soto-Diaz, et autres
Publié: (2021)

Gummatous neurosyphilis in an elderly patient in the Australian outback: a case report
par: Nilesh Anand Devanand, et autres
Publié: (2021)

Recombinant human granulocyte-macrophage colony-stimulating factor: effect of glycosylation on pharmacokinetic parameters
par: Marini,Guillermo, et autres
Publié: (2007)

DOSE-DEPENDENT EFFECTS OF ANTIBACTERIAL ACTIVITY OF SYNTHETIC PEPTIDES ISOLATED FROM GM-CSF ACTIVE CENTER
par: A. V. Zurochka, et autres
Publié: (2014)

Ceftriaxone-induced Encephalopathy: A Pharmacokinetic Approach
par: Laurent Jadot, et autres
Publié: (2021)

Alterations of the serum and CSF ferritin levels and the diagnosis and prognosis of amyotrophic lateral sclerosis
par: Parastou Paydarnia, et autres
Publié: (2021)

Case Report: Prolonged CSF PCR Positivity in a Neonate With GBS Meningitis
par: Nourah Alruqaie, et autres
Publié: (2021)

COMPARATIVE ANALYSIS OF CEREBROSPINAL FLUID ADA LEVELS IN TUBERCULOUS AND NON-TUBERCULOUS MENINGITIS
par: Zahid Ullah, et autres
Publié: (2018)

Why sex matters
par: Josette J Wlaschin, et autres
Publié: (2021)

Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice
par: Julia A Kuhn, et autres
Publié: (2021)

A phase II pilot trial investigating the efficacy and activity of single agent granulocyte macrophage colony-stimulating factor as maintenance approach in castration - resistant prostate cancer patients responding to chemotherapy
par: Chadi Nabhan, et autres
Publié: (2011)

Granulocyte Colony-Stimulating Factor Treatment Before Radiotherapy Protects Against Radiation-Induced Liver Disease in Mice
par: Isalira Peroba Rezende Ramos, et autres
Publié: (2021)

Total Laboratory Automation and Three Shifts Reduce Turnaround Time of Cerebrospinal Fluid Culture Results in the Chinese Clinical Microbiology Laboratory
par: Weili Zhang, et autres
Publié: (2021)

Role of Granulocyte-Macrophage Colony-Stimulating Factor Production by T Cells during <italic toggle="yes">Mycobacterium tuberculosis</italic> Infection
par: Alissa C. Rothchild, et autres
Publié: (2017)

Construction of bicistronic cassette for co-expressing hepatitis B surface antigen and mouse granulocyte-macrophage colony stimulating factor as adjuvant in tobacco plant
par: Sara Mohammadzadeh, et autres
Publié: (2019)

<italic toggle="yes">Cryptococcus deuterogattii</italic> VGIIa Infection Associated with Travel to the Pacific Northwest Outbreak Region in an Anti-Granulocyte-Macrophage Colony-Stimulating Factor Autoantibody-Positive Patient in the United States
par: Shelly Applen Clancey, et autres
Publié: (2019)

Granulocyte Colony-Stimulating Factor for Treatment of Patients with Chronic Traumatic Brain Injury: A Preliminary Pre-Post Study
par: Tsung-Lang Chiu, et autres
Publié: (2021)

Ultra-long-TE arterial spin labeling reveals rapid and brain-wide blood-to-CSF water transport in humans
par: Leonie Petitclerc, et autres
Publié: (2021)

Function of Follicular Cytokines: Roles Played during Maturation, Development and Implantation of Embryo
par: Rafał Adamczak, et autres
Publié: (2021)

Suspected Transverse Myelitis with Normal MRI and CSF Findings in a Patient with Lupus: What to Do? A Case Series and Systematic Review
par: Monahan RC, et autres
Publié: (2020)

Discovery of a novel potentially transforming somatic mutation in CSF2RB gene in breast cancer
par: Mamoon Rashid, et autres
Publié: (2021)

CD69 mediates the protective role of adipose tissue‐derived mesenchymal stem cells against Pseudomonas aeruginosa pulmonary infection
par: Yanshan Jiang, et autres
Publié: (2021)

Anti-PD-1 Immunotherapy Combined With Stereotactic Body Radiation Therapy and GM-CSF as Salvage Therapy in a PD-L1-Positive Patient With Refractory Metastatic Thyroid Hürthle Cell Carcinoma: A Case Report and Literature Review
par: Haihua He, et autres
Publié: (2021)

First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea
par: Jungho Yoon, et autres
Publié: (2021)

Lipegfilgrastim in the management of chemotherapy-induced neutropenia of cancer patients
par: Guariglia R, et autres
Publié: (2016)

Cerebro-Spinal Fluid Leak in Skull Base Reconstruction Using Hadad - Bassagasteguy Flap after Endoscopic Endonasal Transsphenoidal Surgery: A Case Series
par: Jan Paul Formalejo, et autres
Publié: (2021)

Patients with depression display cytokine levels in serum and cerebrospinal fluid similar to patients with diffuse neurological symptoms without a defined diagnosis
par: Hestad KA, et autres
Publié: (2016)

Neurofilament Levels Are Reflecting the Loss of Presynaptic Dopamine Receptors in Movement Disorders
par: Elena Diekämper, et autres
Publié: (2021)

Analisa Business Process Reengineering Dalam Pengembangan Sistem Distribusi Produk Lensa Mata Berbasis Mobile Application
par: Riri Fajriah, et autres
Publié: (2020)

SERUM LEVELS OF HEMOPOIETIC AND ANGIOGENESIS GROWTH FACTORS (IL-5, IL-7, IL-9, FGF-β, G-CSF, VEGF AND PDGF) IN WOMEN WITH UTERINE MYOMA
par: V. I. Konenkov, et autres
Publié: (2018)

Evaluating the Prognostic Role of Monocytopenia in Chemotherapy-Induced Febrile Neutropenia Patients Treated with Granulocyte Colony-Stimulating Factor
par: Alshari O, et autres
Publié: (2021)

IL-6 Quotient (The Ratio of Cerebrospinal Fluid IL-6 to Serum IL-6) as a Biomarker of an Unruptured Intracranial Aneurysm
par: Kamińska J, et autres
Publié: (2021)

Immunobiological properties of granulocytemacrophage colony-stimulating factor and synthetic peptides of his active center
par: A. V. Zurochka, et autres
Publié: (2021)

Elevated circulating magnesium levels in patients with Parkinson’s disease: a meta-analysis
par: Jin X, et autres
Publié: (2018)

Intrauterine Viral Infections: Impact of Inflammation on Fetal Neurodevelopment
par: Sourav Ganguli, et autres
Publié: (2021)

Donor‐derived M2 macrophages attenuate GVHD after allogeneic hematopoietic stem cell transplantation
par: Ryo Hanaki, et autres
Publié: (2021)

Cryptotanshinone ameliorates CUS-induced depressive-like behaviors in mice
par: Wang Kaixin, et autres
Publié: (2021)