Engineered B cells expressing an anti-HIV antibody enable memory retention, isotype switching and clonal expansion
Chronic antiretroviral therapy does not eradicate HIV infection. Here, the authors describe a potentially one-shot alternative by engineering B cells to express anti-HIV antibodies and undergo memory retention, isotype switching and clonal expansion
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Auteurs principaux: | , , , , , , , , , , , |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2020
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Accès en ligne: | https://doaj.org/article/53cea78635c1437b9150abc735992dd8 |
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