Structural analysis of fungal pathogenicity-related casein kinase α subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans

Structural analysis of fungal pathogenicity-related casein kinase α subunit, Cka1, in the human fungal pathogen Cryptococcus neoformans

Abstract CK2α is a constitutively active and highly conserved serine/threonine protein kinase that is involved in the regulation of key cellular metabolic pathways and associated with a variety of tumours and cancers. The most well-known CK2α inhibitor is the human clinical trial candidate CX-4945,...

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Autores principales: Belinda X. Ong, Youngki Yoo, Myeong Gil Han, Jun Bae Park, Myung Kyung Choi, Yeseul Choi, Jeon-Soo Shin, Yong-Sun Bahn, Hyun-Soo Cho
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/53d7b32094a44078b4d9e5fef8d9f205
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