Outcome After Selective Laser Trabeculoplasty for Glaucoma Treatment in a Thai Population

Panrapee Funarunart, Isaraporn Treesit Department of Ophthalmology, Phramongkutklao Hospital, Phramongkutklao College of Medicine, Bangkok, 10400, ThailandCorrespondence: Isaraporn TreesitDepartment of Ophthalmology, Phramongkutklao Hospital, Phramongkutklao College of Medicine, Bangkok, 10400, Thai...

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Autores principales:	Funarunart P, Treesit I
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2021
Materias:	selective laser trabeculoplasty outcome success factors thai Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/53dacb2b9a194973af11a2c03602f51e
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spelling	oai:doaj.org-article:53dacb2b9a194973af11a2c03602f51e2021-12-02T11:39:16ZOutcome After Selective Laser Trabeculoplasty for Glaucoma Treatment in a Thai Population1177-5483https://doaj.org/article/53dacb2b9a194973af11a2c03602f51e2021-03-01T00:00:00Zhttps://www.dovepress.com/outcome-after-selective-laser-trabeculoplasty-for-glaucoma-treatment-i-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Panrapee Funarunart, Isaraporn Treesit Department of Ophthalmology, Phramongkutklao Hospital, Phramongkutklao College of Medicine, Bangkok, 10400, ThailandCorrespondence: Isaraporn TreesitDepartment of Ophthalmology, Phramongkutklao Hospital, Phramongkutklao College of Medicine, Bangkok, 10400, ThailandTel +668 9665 1949Fax +662 354 9309Email isaraporn.treesit@gmail.comPurpose: The study aimed to evaluate the efficacy and predictive factors of success after selective laser trabeculoplasty (SLT) for treating various types of open-angle glaucoma in a Thai population.Design: The study employed a retrospective cohort design.Materials and Methods: The study retrospectively recruited Thai subjects diagnosed with open-angle glaucoma receiving first time selective laser trabeculoplasty. Primary open-angle glaucoma (POAG), ocular hypertension (OHT) and other types of open-angle glaucoma were included. Reduced intraocular pressure (IOP) of 20% or decreased number of antiglaucoma drugs usage after SLT was defined as success. Various parameters were analyzed for association with SLT success.Results: Ninety-six eyes were recruited in the study. Mean pre- and postSLT IOP were 19.31± 3.59 and 15.04± 3.13 mmHg, respectively. IOP decreased significantly in all follow-up visits (p< 0.001). Overall, 59.4% met the treatment endpoint. More than 10% postSLT IOP elevation at 1 hour was the only covariate positively associated with SLT success in both univariate (odds ratio (OR) = 1.042, p = 0.037) and multivariate analyses (OR = 1.040, p = 0.046). Underlying hypertension and preSLT IOP were negatively associated with SLT success in both univariate (OR = 0.970, p = 0.026, OR = 0.955, p < 0.001) and multivariate analysis (OR = 0.970, p = 0.026, OR = 0.991, p < 0.001).Conclusion: IOP significantly decreased as well as the number of antiglaucoma drugs needed after SLT. More than 10% postSLT IOP elevation at 1 hour was a positive predictor whereas systemic hypertension and preSLT IOP were negative predictors of SLT success.Keywords: selective laser trabeculoplasty, outcome, success, factors, ThaiFunarunart PTreesit IDove Medical Pressarticleselective laser trabeculoplastyoutcomesuccessfactorsthaiOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 15, Pp 1193-1200 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	selective laser trabeculoplasty outcome success factors thai Ophthalmology RE1-994
spellingShingle	selective laser trabeculoplasty outcome success factors thai Ophthalmology RE1-994 Funarunart P Treesit I Outcome After Selective Laser Trabeculoplasty for Glaucoma Treatment in a Thai Population
description	Panrapee Funarunart, Isaraporn Treesit Department of Ophthalmology, Phramongkutklao Hospital, Phramongkutklao College of Medicine, Bangkok, 10400, ThailandCorrespondence: Isaraporn TreesitDepartment of Ophthalmology, Phramongkutklao Hospital, Phramongkutklao College of Medicine, Bangkok, 10400, ThailandTel +668 9665 1949Fax +662 354 9309Email isaraporn.treesit@gmail.comPurpose: The study aimed to evaluate the efficacy and predictive factors of success after selective laser trabeculoplasty (SLT) for treating various types of open-angle glaucoma in a Thai population.Design: The study employed a retrospective cohort design.Materials and Methods: The study retrospectively recruited Thai subjects diagnosed with open-angle glaucoma receiving first time selective laser trabeculoplasty. Primary open-angle glaucoma (POAG), ocular hypertension (OHT) and other types of open-angle glaucoma were included. Reduced intraocular pressure (IOP) of 20% or decreased number of antiglaucoma drugs usage after SLT was defined as success. Various parameters were analyzed for association with SLT success.Results: Ninety-six eyes were recruited in the study. Mean pre- and postSLT IOP were 19.31± 3.59 and 15.04± 3.13 mmHg, respectively. IOP decreased significantly in all follow-up visits (p< 0.001). Overall, 59.4% met the treatment endpoint. More than 10% postSLT IOP elevation at 1 hour was the only covariate positively associated with SLT success in both univariate (odds ratio (OR) = 1.042, p = 0.037) and multivariate analyses (OR = 1.040, p = 0.046). Underlying hypertension and preSLT IOP were negatively associated with SLT success in both univariate (OR = 0.970, p = 0.026, OR = 0.955, p < 0.001) and multivariate analysis (OR = 0.970, p = 0.026, OR = 0.991, p < 0.001).Conclusion: IOP significantly decreased as well as the number of antiglaucoma drugs needed after SLT. More than 10% postSLT IOP elevation at 1 hour was a positive predictor whereas systemic hypertension and preSLT IOP were negative predictors of SLT success.Keywords: selective laser trabeculoplasty, outcome, success, factors, Thai
format	article
author	Funarunart P Treesit I
author_facet	Funarunart P Treesit I
author_sort	Funarunart P
title	Outcome After Selective Laser Trabeculoplasty for Glaucoma Treatment in a Thai Population
title_short	Outcome After Selective Laser Trabeculoplasty for Glaucoma Treatment in a Thai Population
title_full	Outcome After Selective Laser Trabeculoplasty for Glaucoma Treatment in a Thai Population
title_fullStr	Outcome After Selective Laser Trabeculoplasty for Glaucoma Treatment in a Thai Population
title_full_unstemmed	Outcome After Selective Laser Trabeculoplasty for Glaucoma Treatment in a Thai Population
title_sort	outcome after selective laser trabeculoplasty for glaucoma treatment in a thai population
publisher	Dove Medical Press
publishDate	2021
url	https://doaj.org/article/53dacb2b9a194973af11a2c03602f51e
work_keys_str_mv	AT funarunartp outcomeafterselectivelasertrabeculoplastyforglaucomatreatmentinathaipopulation AT treesiti outcomeafterselectivelasertrabeculoplastyforglaucomatreatmentinathaipopulation
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Outcome After Selective Laser Trabeculoplasty for Glaucoma Treatment in a Thai Population

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