Thirdhand smoke: Genotoxicity and carcinogenic potential

Thirdhand smoke (THS), the residual tobacco smoke remaining in the environment after tobacco has been smoked, represents a hidden and underestimated public health hazard. Evidence supports its widespread presence in indoor environments. Exposure to secondhand smoke (SHS), a precursor of THS, has bee...

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Autores principales:	Bo Hang, Pin Wang, Yue Zhao, Hang Chang, Jian-Hua Mao, Antoine M. Snijders
Formato:	article
Lenguaje:	EN
Publicado:	KeAi Communications Co., Ltd. 2020
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/53e0f678082342f7bbbb1db7c1de44b2
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id	oai:doaj.org-article:53e0f678082342f7bbbb1db7c1de44b2
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spelling	oai:doaj.org-article:53e0f678082342f7bbbb1db7c1de44b22021-12-02T15:56:17ZThirdhand smoke: Genotoxicity and carcinogenic potential2095-882X10.1016/j.cdtm.2019.08.002https://doaj.org/article/53e0f678082342f7bbbb1db7c1de44b22020-03-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S2095882X19300672https://doaj.org/toc/2095-882XThirdhand smoke (THS), the residual tobacco smoke remaining in the environment after tobacco has been smoked, represents a hidden and underestimated public health hazard. Evidence supports its widespread presence in indoor environments. Exposure to secondhand smoke (SHS), a precursor of THS, has been well documented as a risk factor for human cancers, especially lung cancer. However, the concept of THS as a distinct entity that poses health risks for small children has developed only recently and the associations of THS with cancer risk and other chronic diseases are poorly understood due to limited numbers of studies to date. In this perspective, we mainly summarize all published studies on the genotoxicity and carcinogenic potential of THS exposure. These studies begin to fill the knowledge gap in our understanding of cancer risk of THS. Accumulating data from existing and future studies will help reduce the tobacco-related cancer incidence through changes in lifestyle and tobacco control policies. Keywords: Tobacco, Thirdhand smoke, Tobacco-specific nitrosamines, Genotoxicity, CarcinogenesisBo HangPin WangYue ZhaoHang ChangJian-Hua MaoAntoine M. SnijdersKeAi Communications Co., Ltd.articleMedicine (General)R5-920ENChronic Diseases and Translational Medicine, Vol 6, Iss 1, Pp 27-34 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Bo Hang Pin Wang Yue Zhao Hang Chang Jian-Hua Mao Antoine M. Snijders Thirdhand smoke: Genotoxicity and carcinogenic potential
description	Thirdhand smoke (THS), the residual tobacco smoke remaining in the environment after tobacco has been smoked, represents a hidden and underestimated public health hazard. Evidence supports its widespread presence in indoor environments. Exposure to secondhand smoke (SHS), a precursor of THS, has been well documented as a risk factor for human cancers, especially lung cancer. However, the concept of THS as a distinct entity that poses health risks for small children has developed only recently and the associations of THS with cancer risk and other chronic diseases are poorly understood due to limited numbers of studies to date. In this perspective, we mainly summarize all published studies on the genotoxicity and carcinogenic potential of THS exposure. These studies begin to fill the knowledge gap in our understanding of cancer risk of THS. Accumulating data from existing and future studies will help reduce the tobacco-related cancer incidence through changes in lifestyle and tobacco control policies. Keywords: Tobacco, Thirdhand smoke, Tobacco-specific nitrosamines, Genotoxicity, Carcinogenesis
format	article
author	Bo Hang Pin Wang Yue Zhao Hang Chang Jian-Hua Mao Antoine M. Snijders
author_facet	Bo Hang Pin Wang Yue Zhao Hang Chang Jian-Hua Mao Antoine M. Snijders
author_sort	Bo Hang
title	Thirdhand smoke: Genotoxicity and carcinogenic potential
title_short	Thirdhand smoke: Genotoxicity and carcinogenic potential
title_full	Thirdhand smoke: Genotoxicity and carcinogenic potential
title_fullStr	Thirdhand smoke: Genotoxicity and carcinogenic potential
title_full_unstemmed	Thirdhand smoke: Genotoxicity and carcinogenic potential
title_sort	thirdhand smoke: genotoxicity and carcinogenic potential
publisher	KeAi Communications Co., Ltd.
publishDate	2020
url	https://doaj.org/article/53e0f678082342f7bbbb1db7c1de44b2
work_keys_str_mv	AT bohang thirdhandsmokegenotoxicityandcarcinogenicpotential AT pinwang thirdhandsmokegenotoxicityandcarcinogenicpotential AT yuezhao thirdhandsmokegenotoxicityandcarcinogenicpotential AT hangchang thirdhandsmokegenotoxicityandcarcinogenicpotential AT jianhuamao thirdhandsmokegenotoxicityandcarcinogenicpotential AT antoinemsnijders thirdhandsmokegenotoxicityandcarcinogenicpotential
_version_	1718385391029977088

Thirdhand smoke: Genotoxicity and carcinogenic potential

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