An integrated genomic regulatory network of virulence-related transcriptional factors in Pseudomonas aeruginosa

An integrated genomic regulatory network of virulence-related transcriptional factors in Pseudomonas aeruginosa

The virulence of Pseudomonas aeruginosa is regulated by many transcriptional factors (TFs). Here, the authors study the crosstalk between 20 key virulence-related TFs, validate 347 functional target genes, and describe the regulatory relationships of the 20 TFs with their targets in a network that i...

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Autores principales: Hao Huang, Xiaolong Shao, Yingpeng Xie, Tingting Wang, Yingchao Zhang, Xin Wang, Xin Deng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/53e9d0b2eb8f4dd69dbb59662664a09e
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spelling oai:doaj.org-article:53e9d0b2eb8f4dd69dbb59662664a09e2021-12-02T14:38:38ZAn integrated genomic regulatory network of virulence-related transcriptional factors in Pseudomonas aeruginosa10.1038/s41467-019-10778-w2041-1723https://doaj.org/article/53e9d0b2eb8f4dd69dbb59662664a09e2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10778-whttps://doaj.org/toc/2041-1723The virulence of Pseudomonas aeruginosa is regulated by many transcriptional factors (TFs). Here, the authors study the crosstalk between 20 key virulence-related TFs, validate 347 functional target genes, and describe the regulatory relationships of the 20 TFs with their targets in a network that is available as an online platform.Hao HuangXiaolong ShaoYingpeng XieTingting WangYingchao ZhangXin WangXin DengNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hao Huang
Xiaolong Shao
Yingpeng Xie
Tingting Wang
Yingchao Zhang
Xin Wang
Xin Deng
An integrated genomic regulatory network of virulence-related transcriptional factors in Pseudomonas aeruginosa
description The virulence of Pseudomonas aeruginosa is regulated by many transcriptional factors (TFs). Here, the authors study the crosstalk between 20 key virulence-related TFs, validate 347 functional target genes, and describe the regulatory relationships of the 20 TFs with their targets in a network that is available as an online platform.
format article
author Hao Huang
Xiaolong Shao
Yingpeng Xie
Tingting Wang
Yingchao Zhang
Xin Wang
Xin Deng
author_facet Hao Huang
Xiaolong Shao
Yingpeng Xie
Tingting Wang
Yingchao Zhang
Xin Wang
Xin Deng
author_sort Hao Huang
title An integrated genomic regulatory network of virulence-related transcriptional factors in Pseudomonas aeruginosa
title_short An integrated genomic regulatory network of virulence-related transcriptional factors in Pseudomonas aeruginosa
title_full An integrated genomic regulatory network of virulence-related transcriptional factors in Pseudomonas aeruginosa
title_fullStr An integrated genomic regulatory network of virulence-related transcriptional factors in Pseudomonas aeruginosa
title_full_unstemmed An integrated genomic regulatory network of virulence-related transcriptional factors in Pseudomonas aeruginosa
title_sort integrated genomic regulatory network of virulence-related transcriptional factors in pseudomonas aeruginosa
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/53e9d0b2eb8f4dd69dbb59662664a09e
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