Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.

To identify genetic loci influencing central obesity and fat distribution, we performed a meta-analysis of 16 genome-wide association studies (GWAS, N = 38,580) informative for adult waist circumference (WC) and waist-hip ratio (WHR). We selected 26 SNPs for follow-up, for which the evidence of asso...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Cecilia M Lindgren, Iris M Heid, Joshua C Randall, Claudia Lamina, Valgerdur Steinthorsdottir, Lu Qi, Elizabeth K Speliotes, Gudmar Thorleifsson, Cristen J Willer, Blanca M Herrera, Anne U Jackson, Noha Lim, Paul Scheet, Nicole Soranzo, Najaf Amin, Yurii S Aulchenko, John C Chambers, Alexander Drong, Jian'an Luan, Helen N Lyon, Fernando Rivadeneira, Serena Sanna, Nicholas J Timpson, M Carola Zillikens, Jing Hua Zhao, Peter Almgren, Stefania Bandinelli, Amanda J Bennett, Richard N Bergman, Lori L Bonnycastle, Suzannah J Bumpstead, Stephen J Chanock, Lynn Cherkas, Peter Chines, Lachlan Coin, Cyrus Cooper, Gabriel Crawford, Angela Doering, Anna Dominiczak, Alex S F Doney, Shah Ebrahim, Paul Elliott, Michael R Erdos, Karol Estrada, Luigi Ferrucci, Guido Fischer, Nita G Forouhi, Christian Gieger, Harald Grallert, Christopher J Groves, Scott Grundy, Candace Guiducci, David Hadley, Anders Hamsten, Aki S Havulinna, Albert Hofman, Rolf Holle, John W Holloway, Thomas Illig, Bo Isomaa, Leonie C Jacobs, Karen Jameson, Pekka Jousilahti, Fredrik Karpe, Johanna Kuusisto, Jaana Laitinen, G Mark Lathrop, Debbie A Lawlor, Massimo Mangino, Wendy L McArdle, Thomas Meitinger, Mario A Morken, Andrew P Morris, Patricia Munroe, Narisu Narisu, Anna Nordström, Peter Nordström, Ben A Oostra, Colin N A Palmer, Felicity Payne, John F Peden, Inga Prokopenko, Frida Renström, Aimo Ruokonen, Veikko Salomaa, Manjinder S Sandhu, Laura J Scott, Angelo Scuteri, Kaisa Silander, Kijoung Song, Xin Yuan, Heather M Stringham, Amy J Swift, Tiinamaija Tuomi, Manuela Uda, Peter Vollenweider, Gerard Waeber, Chris Wallace, G Bragi Walters, Michael N Weedon, Wellcome Trust Case Control Consortium, Jacqueline C M Witteman, Cuilin Zhang, Weihua Zhang, Mark J Caulfield, Francis S Collins, George Davey Smith, Ian N M Day, Paul W Franks, Andrew T Hattersley, Frank B Hu, Marjo-Riitta Jarvelin, Augustine Kong, Jaspal S Kooner, Markku Laakso, Edward Lakatta, Vincent Mooser, Andrew D Morris, Leena Peltonen, Nilesh J Samani, Timothy D Spector, David P Strachan, Toshiko Tanaka, Jaakko Tuomilehto, André G Uitterlinden, Cornelia M van Duijn, Nicholas J Wareham, Hugh Watkins, Procardis Consortia, Dawn M Waterworth, Michael Boehnke, Panos Deloukas, Leif Groop, David J Hunter, Unnur Thorsteinsdottir, David Schlessinger, H-Erich Wichmann, Timothy M Frayling, Gonçalo R Abecasis, Joel N Hirschhorn, Ruth J F Loos, Kari Stefansson, Karen L Mohlke, Inês Barroso, Mark I McCarthy, Giant Consortium
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2009
Materias:	Genetics QH426-470
Acceso en línea:	https://doaj.org/article/53eb782f29cd4abcb81556de526eb32f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:53eb782f29cd4abcb81556de526eb32f
record_format	dspace
spelling	oai:doaj.org-article:53eb782f29cd4abcb81556de526eb32f2021-11-25T05:53:19ZGenome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.1553-73901553-740410.1371/journal.pgen.1000508https://doaj.org/article/53eb782f29cd4abcb81556de526eb32f2009-06-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19557161/pdf/?tool=EBIhttps://doaj.org/toc/1553-7390https://doaj.org/toc/1553-7404To identify genetic loci influencing central obesity and fat distribution, we performed a meta-analysis of 16 genome-wide association studies (GWAS, N = 38,580) informative for adult waist circumference (WC) and waist-hip ratio (WHR). We selected 26 SNPs for follow-up, for which the evidence of association with measures of central adiposity (WC and/or WHR) was strong and disproportionate to that for overall adiposity or height. Follow-up studies in a maximum of 70,689 individuals identified two loci strongly associated with measures of central adiposity; these map near TFAP2B (WC, P = 1.9x10(-11)) and MSRA (WC, P = 8.9x10(-9)). A third locus, near LYPLAL1, was associated with WHR in women only (P = 2.6x10(-8)). The variants near TFAP2B appear to influence central adiposity through an effect on overall obesity/fat-mass, whereas LYPLAL1 displays a strong female-only association with fat distribution. By focusing on anthropometric measures of central obesity and fat distribution, we have identified three loci implicated in the regulation of human adiposity.Cecilia M LindgrenIris M HeidJoshua C RandallClaudia LaminaValgerdur SteinthorsdottirLu QiElizabeth K SpeliotesGudmar ThorleifssonCristen J WillerBlanca M HerreraAnne U JacksonNoha LimPaul ScheetNicole SoranzoNajaf AminYurii S AulchenkoJohn C ChambersAlexander DrongJian'an LuanHelen N LyonFernando RivadeneiraSerena SannaNicholas J TimpsonM Carola ZillikensJing Hua ZhaoPeter AlmgrenStefania BandinelliAmanda J BennettRichard N BergmanLori L BonnycastleSuzannah J BumpsteadStephen J ChanockLynn CherkasPeter ChinesLachlan CoinCyrus CooperGabriel CrawfordAngela DoeringAnna DominiczakAlex S F DoneyShah EbrahimPaul ElliottMichael R ErdosKarol EstradaLuigi FerrucciGuido FischerNita G ForouhiChristian GiegerHarald GrallertChristopher J GrovesScott GrundyCandace GuiducciDavid HadleyAnders HamstenAki S HavulinnaAlbert HofmanRolf HolleJohn W HollowayThomas IlligBo IsomaaLeonie C JacobsKaren JamesonPekka JousilahtiFredrik KarpeJohanna KuusistoJaana LaitinenG Mark LathropDebbie A LawlorMassimo ManginoWendy L McArdleThomas MeitingerMario A MorkenAndrew P MorrisPatricia MunroeNarisu NarisuAnna NordströmPeter NordströmBen A OostraColin N A PalmerFelicity PayneJohn F PedenInga ProkopenkoFrida RenströmAimo RuokonenVeikko SalomaaManjinder S SandhuLaura J ScottAngelo ScuteriKaisa SilanderKijoung SongXin YuanHeather M StringhamAmy J SwiftTiinamaija TuomiManuela UdaPeter VollenweiderGerard WaeberChris WallaceG Bragi WaltersMichael N WeedonWellcome Trust Case Control ConsortiumJacqueline C M WittemanCuilin ZhangWeihua ZhangMark J CaulfieldFrancis S CollinsGeorge Davey SmithIan N M DayPaul W FranksAndrew T HattersleyFrank B HuMarjo-Riitta JarvelinAugustine KongJaspal S KoonerMarkku LaaksoEdward LakattaVincent MooserAndrew D MorrisLeena PeltonenNilesh J SamaniTimothy D SpectorDavid P StrachanToshiko TanakaJaakko TuomilehtoAndré G UitterlindenCornelia M van DuijnNicholas J WarehamHugh WatkinsProcardis ConsortiaDawn M WaterworthMichael BoehnkePanos DeloukasLeif GroopDavid J HunterUnnur ThorsteinsdottirDavid SchlessingerH-Erich WichmannTimothy M FraylingGonçalo R AbecasisJoel N HirschhornRuth J F LoosKari StefanssonKaren L MohlkeInês BarrosoMark I McCarthyGiant ConsortiumPublic Library of Science (PLoS)articleGeneticsQH426-470ENPLoS Genetics, Vol 5, Iss 6, p e1000508 (2009)
institution	DOAJ
collection	DOAJ
language	EN
topic	Genetics QH426-470
spellingShingle	Genetics QH426-470 Cecilia M Lindgren Iris M Heid Joshua C Randall Claudia Lamina Valgerdur Steinthorsdottir Lu Qi Elizabeth K Speliotes Gudmar Thorleifsson Cristen J Willer Blanca M Herrera Anne U Jackson Noha Lim Paul Scheet Nicole Soranzo Najaf Amin Yurii S Aulchenko John C Chambers Alexander Drong Jian'an Luan Helen N Lyon Fernando Rivadeneira Serena Sanna Nicholas J Timpson M Carola Zillikens Jing Hua Zhao Peter Almgren Stefania Bandinelli Amanda J Bennett Richard N Bergman Lori L Bonnycastle Suzannah J Bumpstead Stephen J Chanock Lynn Cherkas Peter Chines Lachlan Coin Cyrus Cooper Gabriel Crawford Angela Doering Anna Dominiczak Alex S F Doney Shah Ebrahim Paul Elliott Michael R Erdos Karol Estrada Luigi Ferrucci Guido Fischer Nita G Forouhi Christian Gieger Harald Grallert Christopher J Groves Scott Grundy Candace Guiducci David Hadley Anders Hamsten Aki S Havulinna Albert Hofman Rolf Holle John W Holloway Thomas Illig Bo Isomaa Leonie C Jacobs Karen Jameson Pekka Jousilahti Fredrik Karpe Johanna Kuusisto Jaana Laitinen G Mark Lathrop Debbie A Lawlor Massimo Mangino Wendy L McArdle Thomas Meitinger Mario A Morken Andrew P Morris Patricia Munroe Narisu Narisu Anna Nordström Peter Nordström Ben A Oostra Colin N A Palmer Felicity Payne John F Peden Inga Prokopenko Frida Renström Aimo Ruokonen Veikko Salomaa Manjinder S Sandhu Laura J Scott Angelo Scuteri Kaisa Silander Kijoung Song Xin Yuan Heather M Stringham Amy J Swift Tiinamaija Tuomi Manuela Uda Peter Vollenweider Gerard Waeber Chris Wallace G Bragi Walters Michael N Weedon Wellcome Trust Case Control Consortium Jacqueline C M Witteman Cuilin Zhang Weihua Zhang Mark J Caulfield Francis S Collins George Davey Smith Ian N M Day Paul W Franks Andrew T Hattersley Frank B Hu Marjo-Riitta Jarvelin Augustine Kong Jaspal S Kooner Markku Laakso Edward Lakatta Vincent Mooser Andrew D Morris Leena Peltonen Nilesh J Samani Timothy D Spector David P Strachan Toshiko Tanaka Jaakko Tuomilehto André G Uitterlinden Cornelia M van Duijn Nicholas J Wareham Hugh Watkins Procardis Consortia Dawn M Waterworth Michael Boehnke Panos Deloukas Leif Groop David J Hunter Unnur Thorsteinsdottir David Schlessinger H-Erich Wichmann Timothy M Frayling Gonçalo R Abecasis Joel N Hirschhorn Ruth J F Loos Kari Stefansson Karen L Mohlke Inês Barroso Mark I McCarthy Giant Consortium Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
description	To identify genetic loci influencing central obesity and fat distribution, we performed a meta-analysis of 16 genome-wide association studies (GWAS, N = 38,580) informative for adult waist circumference (WC) and waist-hip ratio (WHR). We selected 26 SNPs for follow-up, for which the evidence of association with measures of central adiposity (WC and/or WHR) was strong and disproportionate to that for overall adiposity or height. Follow-up studies in a maximum of 70,689 individuals identified two loci strongly associated with measures of central adiposity; these map near TFAP2B (WC, P = 1.9x10(-11)) and MSRA (WC, P = 8.9x10(-9)). A third locus, near LYPLAL1, was associated with WHR in women only (P = 2.6x10(-8)). The variants near TFAP2B appear to influence central adiposity through an effect on overall obesity/fat-mass, whereas LYPLAL1 displays a strong female-only association with fat distribution. By focusing on anthropometric measures of central obesity and fat distribution, we have identified three loci implicated in the regulation of human adiposity.
format	article
author	Cecilia M Lindgren Iris M Heid Joshua C Randall Claudia Lamina Valgerdur Steinthorsdottir Lu Qi Elizabeth K Speliotes Gudmar Thorleifsson Cristen J Willer Blanca M Herrera Anne U Jackson Noha Lim Paul Scheet Nicole Soranzo Najaf Amin Yurii S Aulchenko John C Chambers Alexander Drong Jian'an Luan Helen N Lyon Fernando Rivadeneira Serena Sanna Nicholas J Timpson M Carola Zillikens Jing Hua Zhao Peter Almgren Stefania Bandinelli Amanda J Bennett Richard N Bergman Lori L Bonnycastle Suzannah J Bumpstead Stephen J Chanock Lynn Cherkas Peter Chines Lachlan Coin Cyrus Cooper Gabriel Crawford Angela Doering Anna Dominiczak Alex S F Doney Shah Ebrahim Paul Elliott Michael R Erdos Karol Estrada Luigi Ferrucci Guido Fischer Nita G Forouhi Christian Gieger Harald Grallert Christopher J Groves Scott Grundy Candace Guiducci David Hadley Anders Hamsten Aki S Havulinna Albert Hofman Rolf Holle John W Holloway Thomas Illig Bo Isomaa Leonie C Jacobs Karen Jameson Pekka Jousilahti Fredrik Karpe Johanna Kuusisto Jaana Laitinen G Mark Lathrop Debbie A Lawlor Massimo Mangino Wendy L McArdle Thomas Meitinger Mario A Morken Andrew P Morris Patricia Munroe Narisu Narisu Anna Nordström Peter Nordström Ben A Oostra Colin N A Palmer Felicity Payne John F Peden Inga Prokopenko Frida Renström Aimo Ruokonen Veikko Salomaa Manjinder S Sandhu Laura J Scott Angelo Scuteri Kaisa Silander Kijoung Song Xin Yuan Heather M Stringham Amy J Swift Tiinamaija Tuomi Manuela Uda Peter Vollenweider Gerard Waeber Chris Wallace G Bragi Walters Michael N Weedon Wellcome Trust Case Control Consortium Jacqueline C M Witteman Cuilin Zhang Weihua Zhang Mark J Caulfield Francis S Collins George Davey Smith Ian N M Day Paul W Franks Andrew T Hattersley Frank B Hu Marjo-Riitta Jarvelin Augustine Kong Jaspal S Kooner Markku Laakso Edward Lakatta Vincent Mooser Andrew D Morris Leena Peltonen Nilesh J Samani Timothy D Spector David P Strachan Toshiko Tanaka Jaakko Tuomilehto André G Uitterlinden Cornelia M van Duijn Nicholas J Wareham Hugh Watkins Procardis Consortia Dawn M Waterworth Michael Boehnke Panos Deloukas Leif Groop David J Hunter Unnur Thorsteinsdottir David Schlessinger H-Erich Wichmann Timothy M Frayling Gonçalo R Abecasis Joel N Hirschhorn Ruth J F Loos Kari Stefansson Karen L Mohlke Inês Barroso Mark I McCarthy Giant Consortium
author_facet	Cecilia M Lindgren Iris M Heid Joshua C Randall Claudia Lamina Valgerdur Steinthorsdottir Lu Qi Elizabeth K Speliotes Gudmar Thorleifsson Cristen J Willer Blanca M Herrera Anne U Jackson Noha Lim Paul Scheet Nicole Soranzo Najaf Amin Yurii S Aulchenko John C Chambers Alexander Drong Jian'an Luan Helen N Lyon Fernando Rivadeneira Serena Sanna Nicholas J Timpson M Carola Zillikens Jing Hua Zhao Peter Almgren Stefania Bandinelli Amanda J Bennett Richard N Bergman Lori L Bonnycastle Suzannah J Bumpstead Stephen J Chanock Lynn Cherkas Peter Chines Lachlan Coin Cyrus Cooper Gabriel Crawford Angela Doering Anna Dominiczak Alex S F Doney Shah Ebrahim Paul Elliott Michael R Erdos Karol Estrada Luigi Ferrucci Guido Fischer Nita G Forouhi Christian Gieger Harald Grallert Christopher J Groves Scott Grundy Candace Guiducci David Hadley Anders Hamsten Aki S Havulinna Albert Hofman Rolf Holle John W Holloway Thomas Illig Bo Isomaa Leonie C Jacobs Karen Jameson Pekka Jousilahti Fredrik Karpe Johanna Kuusisto Jaana Laitinen G Mark Lathrop Debbie A Lawlor Massimo Mangino Wendy L McArdle Thomas Meitinger Mario A Morken Andrew P Morris Patricia Munroe Narisu Narisu Anna Nordström Peter Nordström Ben A Oostra Colin N A Palmer Felicity Payne John F Peden Inga Prokopenko Frida Renström Aimo Ruokonen Veikko Salomaa Manjinder S Sandhu Laura J Scott Angelo Scuteri Kaisa Silander Kijoung Song Xin Yuan Heather M Stringham Amy J Swift Tiinamaija Tuomi Manuela Uda Peter Vollenweider Gerard Waeber Chris Wallace G Bragi Walters Michael N Weedon Wellcome Trust Case Control Consortium Jacqueline C M Witteman Cuilin Zhang Weihua Zhang Mark J Caulfield Francis S Collins George Davey Smith Ian N M Day Paul W Franks Andrew T Hattersley Frank B Hu Marjo-Riitta Jarvelin Augustine Kong Jaspal S Kooner Markku Laakso Edward Lakatta Vincent Mooser Andrew D Morris Leena Peltonen Nilesh J Samani Timothy D Spector David P Strachan Toshiko Tanaka Jaakko Tuomilehto André G Uitterlinden Cornelia M van Duijn Nicholas J Wareham Hugh Watkins Procardis Consortia Dawn M Waterworth Michael Boehnke Panos Deloukas Leif Groop David J Hunter Unnur Thorsteinsdottir David Schlessinger H-Erich Wichmann Timothy M Frayling Gonçalo R Abecasis Joel N Hirschhorn Ruth J F Loos Kari Stefansson Karen L Mohlke Inês Barroso Mark I McCarthy Giant Consortium
author_sort	Cecilia M Lindgren
title	Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
title_short	Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
title_full	Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
title_fullStr	Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
title_full_unstemmed	Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
title_sort	genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution.
publisher	Public Library of Science (PLoS)
publishDate	2009
url	https://doaj.org/article/53eb782f29cd4abcb81556de526eb32f
work_keys_str_mv	AT ceciliamlindgren genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT irismheid genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT joshuacrandall genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT claudialamina genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT valgerdursteinthorsdottir genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT luqi genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT elizabethkspeliotes genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT gudmarthorleifsson genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT cristenjwiller genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT blancamherrera genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT anneujackson genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT nohalim genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT paulscheet genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT nicolesoranzo genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT najafamin genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT yuriisaulchenko genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT johncchambers genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT alexanderdrong genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT jiananluan genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT helennlyon genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT fernandorivadeneira genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT serenasanna genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT nicholasjtimpson genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT mcarolazillikens genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT jinghuazhao genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT peteralmgren genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT stefaniabandinelli genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT amandajbennett genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT richardnbergman genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT lorilbonnycastle genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT suzannahjbumpstead genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT stephenjchanock genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT lynncherkas genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT peterchines genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT lachlancoin genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT cyruscooper genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT gabrielcrawford genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT angeladoering genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT annadominiczak genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT alexsfdoney genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT shahebrahim genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT paulelliott genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT michaelrerdos genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT karolestrada genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT luigiferrucci genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT guidofischer genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT nitagforouhi genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT christiangieger genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT haraldgrallert genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT christopherjgroves genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT scottgrundy genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT candaceguiducci genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT davidhadley genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT andershamsten genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT akishavulinna genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT alberthofman genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT rolfholle genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT johnwholloway genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT thomasillig genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT boisomaa genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT leoniecjacobs genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT karenjameson genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT pekkajousilahti genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT fredrikkarpe genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT johannakuusisto genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT jaanalaitinen genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT gmarklathrop genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT debbiealawlor genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT massimomangino genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT wendylmcardle genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT thomasmeitinger genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT marioamorken genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT andrewpmorris genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT patriciamunroe genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT narisunarisu genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT annanordstrom genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT peternordstrom genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT benaoostra genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT colinnapalmer genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT felicitypayne genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT johnfpeden genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT ingaprokopenko genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT fridarenstrom genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT aimoruokonen genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT veikkosalomaa genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT manjinderssandhu genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT laurajscott genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT angeloscuteri genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT kaisasilander genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT kijoungsong genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT xinyuan genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT heathermstringham genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT amyjswift genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT tiinamaijatuomi genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT manuelauda genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT petervollenweider genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT gerardwaeber genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT chriswallace genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT gbragiwalters genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT michaelnweedon genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT wellcometrustcasecontrolconsortium genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT jacquelinecmwitteman genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT cuilinzhang genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT weihuazhang genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT markjcaulfield genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT francisscollins genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT georgedaveysmith genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT iannmday genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT paulwfranks genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT andrewthattersley genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT frankbhu genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT marjoriittajarvelin genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT augustinekong genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT jaspalskooner genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT markkulaakso genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT edwardlakatta genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT vincentmooser genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT andrewdmorris genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT leenapeltonen genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT nileshjsamani genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT timothydspector genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT davidpstrachan genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT toshikotanaka genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT jaakkotuomilehto genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT andreguitterlinden genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT corneliamvanduijn genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT nicholasjwareham genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT hughwatkins genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT procardisconsortia genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT dawnmwaterworth genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT michaelboehnke genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT panosdeloukas genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT leifgroop genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT davidjhunter genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT unnurthorsteinsdottir genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT davidschlessinger genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT herichwichmann genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT timothymfrayling genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT goncalorabecasis genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT joelnhirschhorn genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT ruthjfloos genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT karistefansson genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT karenlmohlke genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT inesbarroso genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT markimccarthy genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution AT giantconsortium genomewideassociationscanmetaanalysisidentifiesthreelociinfluencingadiposityandfatdistribution
_version_	1718414400237338624

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.

Ejemplares similares