Cigarette smoke-induced impairment of autophagy in macrophages increases galectin-8 and inflammation

Cigarette smoke-induced impairment of autophagy in macrophages increases galectin-8 and inflammation

Abstract Cigarette smoke impairs autophagy, an intracellular protein degradation system, but the consequences of this defect have not been fully elucidated, especially in macrophages. Dysfunctional alveolar macrophages play an important role in chronic obstructive pulmonary disease (COPD). Here we s...

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Autores principales: Yuta Kono, Thomas Colley, Masako To, Andriana I. Papaioannou, Nicolas Mercado, Jonathan R. Baker, Yasuo To, Shinji Abe, Kosuke Haruki, Kazuhiro Ito, Peter J. Barnes
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/53ee665d1b754109b38eb255b8f98a81
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