Synthesis and biological characterization of silver nanoparticles derived from the cyanobacterium Oscillatoria limnetica

Abstract Using aqueous cyanobacterial extracts in the synthesis of silver nanoparticle is looked as green, ecofriendly, low priced biotechnology that gives advancement over both chemical and physical methods. In the current study, an aqueous extract of Oscillatoria limnetica fresh biomass was used f...

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Autores principales:	Ragaa A. Hamouda, Mervat H. Hussein, Rasha A. Abo-elmagd, Salwa S. Bawazir
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/53f1babc0a274db4a9a3437a97e19bdb
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spelling	oai:doaj.org-article:53f1babc0a274db4a9a3437a97e19bdb2021-12-02T15:08:07ZSynthesis and biological characterization of silver nanoparticles derived from the cyanobacterium Oscillatoria limnetica10.1038/s41598-019-49444-y2045-2322https://doaj.org/article/53f1babc0a274db4a9a3437a97e19bdb2019-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-019-49444-yhttps://doaj.org/toc/2045-2322Abstract Using aqueous cyanobacterial extracts in the synthesis of silver nanoparticle is looked as green, ecofriendly, low priced biotechnology that gives advancement over both chemical and physical methods. In the current study, an aqueous extract of Oscillatoria limnetica fresh biomass was used for the green synthesis of Ag-NPs, since O. limnetica extract plays a dual part in both reducing and stabilizing Oscillatoria-silver nanoparticles (O-AgNPs). The UV-Visible absorption spectrum, Fourier transforms infrared (FT-IR), transmission electron microscopy (TEM) and scanning electron microscope (SEM) were achieved for confirming and characterizing the biosynthesized O-AgNPs. TEM images detected the quasi-spherical Ag-NPs shape with diverse size ranged within 3.30–17.97 nm. FT-IR analysis demonstrated the presence of free amino groups in addition to sulfur containing amino acid derivatives acting as stabilizing agents as well as the presence of either sulfur or phosphorus functional groups which possibly attaches silver. In this study, synthesized Ag-NPs exhibited strong antibacterial activity against multidrug-resistant bacteria (Escherichia coli and Bacillus cereus) as well as cytotoxic effects against both human breast (MCF-7) cell line giving IC50 (6.147 µg/ml) and human colon cancer (HCT-116) cell line giving IC50 (5.369 µg/ml). Hemolytic activity of Ag-NPs was investigated and confirmed as being non- toxic to human RBCs in low concentrations.Ragaa A. HamoudaMervat H. HusseinRasha A. Abo-elmagdSalwa S. BawazirNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ragaa A. Hamouda Mervat H. Hussein Rasha A. Abo-elmagd Salwa S. Bawazir Synthesis and biological characterization of silver nanoparticles derived from the cyanobacterium Oscillatoria limnetica
description	Abstract Using aqueous cyanobacterial extracts in the synthesis of silver nanoparticle is looked as green, ecofriendly, low priced biotechnology that gives advancement over both chemical and physical methods. In the current study, an aqueous extract of Oscillatoria limnetica fresh biomass was used for the green synthesis of Ag-NPs, since O. limnetica extract plays a dual part in both reducing and stabilizing Oscillatoria-silver nanoparticles (O-AgNPs). The UV-Visible absorption spectrum, Fourier transforms infrared (FT-IR), transmission electron microscopy (TEM) and scanning electron microscope (SEM) were achieved for confirming and characterizing the biosynthesized O-AgNPs. TEM images detected the quasi-spherical Ag-NPs shape with diverse size ranged within 3.30–17.97 nm. FT-IR analysis demonstrated the presence of free amino groups in addition to sulfur containing amino acid derivatives acting as stabilizing agents as well as the presence of either sulfur or phosphorus functional groups which possibly attaches silver. In this study, synthesized Ag-NPs exhibited strong antibacterial activity against multidrug-resistant bacteria (Escherichia coli and Bacillus cereus) as well as cytotoxic effects against both human breast (MCF-7) cell line giving IC50 (6.147 µg/ml) and human colon cancer (HCT-116) cell line giving IC50 (5.369 µg/ml). Hemolytic activity of Ag-NPs was investigated and confirmed as being non- toxic to human RBCs in low concentrations.
format	article
author	Ragaa A. Hamouda Mervat H. Hussein Rasha A. Abo-elmagd Salwa S. Bawazir
author_facet	Ragaa A. Hamouda Mervat H. Hussein Rasha A. Abo-elmagd Salwa S. Bawazir
author_sort	Ragaa A. Hamouda
title	Synthesis and biological characterization of silver nanoparticles derived from the cyanobacterium Oscillatoria limnetica
title_short	Synthesis and biological characterization of silver nanoparticles derived from the cyanobacterium Oscillatoria limnetica
title_full	Synthesis and biological characterization of silver nanoparticles derived from the cyanobacterium Oscillatoria limnetica
title_fullStr	Synthesis and biological characterization of silver nanoparticles derived from the cyanobacterium Oscillatoria limnetica
title_full_unstemmed	Synthesis and biological characterization of silver nanoparticles derived from the cyanobacterium Oscillatoria limnetica
title_sort	synthesis and biological characterization of silver nanoparticles derived from the cyanobacterium oscillatoria limnetica
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/53f1babc0a274db4a9a3437a97e19bdb
work_keys_str_mv	AT ragaaahamouda synthesisandbiologicalcharacterizationofsilvernanoparticlesderivedfromthecyanobacteriumoscillatorialimnetica AT mervathhussein synthesisandbiologicalcharacterizationofsilvernanoparticlesderivedfromthecyanobacteriumoscillatorialimnetica AT rashaaaboelmagd synthesisandbiologicalcharacterizationofsilvernanoparticlesderivedfromthecyanobacteriumoscillatorialimnetica AT salwasbawazir synthesisandbiologicalcharacterizationofsilvernanoparticlesderivedfromthecyanobacteriumoscillatorialimnetica
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Synthesis and biological characterization of silver nanoparticles derived from the cyanobacterium Oscillatoria limnetica

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