A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA

Riboswitches consist of an aptamer domain and expression platform, which senses a signal and regulates gene expression, respectively. Here the authors show that the expression platform of a SAM-I riboswitch from the Gram-negative bacteria can sense and bind uncharged an initiator Met tRNA to control...

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Autores principales: Dong-Jie Tang, Xinyu Du, Qiang Shi, Jian-Ling Zhang, Yuan-Ping He, Yan-Miao Chen, Zhenhua Ming, Dan Wang, Wan-Ying Zhong, Yu-Wei Liang, Jin-Yang Liu, Jian-Ming Huang, Yun-Shi Zhong, Shi-Qi An, Hongzhou Gu, Ji-Liang Tang
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/53f78559583c4245b33bf8e5f4e78bc0
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spelling oai:doaj.org-article:53f78559583c4245b33bf8e5f4e78bc02021-12-02T15:03:03ZA SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA10.1038/s41467-020-16417-z2041-1723https://doaj.org/article/53f78559583c4245b33bf8e5f4e78bc02020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16417-zhttps://doaj.org/toc/2041-1723Riboswitches consist of an aptamer domain and expression platform, which senses a signal and regulates gene expression, respectively. Here the authors show that the expression platform of a SAM-I riboswitch from the Gram-negative bacteria can sense and bind uncharged an initiator Met tRNA to control the met operon.Dong-Jie TangXinyu DuQiang ShiJian-Ling ZhangYuan-Ping HeYan-Miao ChenZhenhua MingDan WangWan-Ying ZhongYu-Wei LiangJin-Yang LiuJian-Ming HuangYun-Shi ZhongShi-Qi AnHongzhou GuJi-Liang TangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dong-Jie Tang
Xinyu Du
Qiang Shi
Jian-Ling Zhang
Yuan-Ping He
Yan-Miao Chen
Zhenhua Ming
Dan Wang
Wan-Ying Zhong
Yu-Wei Liang
Jin-Yang Liu
Jian-Ming Huang
Yun-Shi Zhong
Shi-Qi An
Hongzhou Gu
Ji-Liang Tang
A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA
description Riboswitches consist of an aptamer domain and expression platform, which senses a signal and regulates gene expression, respectively. Here the authors show that the expression platform of a SAM-I riboswitch from the Gram-negative bacteria can sense and bind uncharged an initiator Met tRNA to control the met operon.
format article
author Dong-Jie Tang
Xinyu Du
Qiang Shi
Jian-Ling Zhang
Yuan-Ping He
Yan-Miao Chen
Zhenhua Ming
Dan Wang
Wan-Ying Zhong
Yu-Wei Liang
Jin-Yang Liu
Jian-Ming Huang
Yun-Shi Zhong
Shi-Qi An
Hongzhou Gu
Ji-Liang Tang
author_facet Dong-Jie Tang
Xinyu Du
Qiang Shi
Jian-Ling Zhang
Yuan-Ping He
Yan-Miao Chen
Zhenhua Ming
Dan Wang
Wan-Ying Zhong
Yu-Wei Liang
Jin-Yang Liu
Jian-Ming Huang
Yun-Shi Zhong
Shi-Qi An
Hongzhou Gu
Ji-Liang Tang
author_sort Dong-Jie Tang
title A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA
title_short A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA
title_full A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA
title_fullStr A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA
title_full_unstemmed A SAM-I riboswitch with the ability to sense and respond to uncharged initiator tRNA
title_sort sam-i riboswitch with the ability to sense and respond to uncharged initiator trna
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/53f78559583c4245b33bf8e5f4e78bc0
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