Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors

The role of gastrin related peptide (GRP+) neurons in itch is debated. Here, the authors generate a conditional knock-in mouse to label and manipulate GRP expressing DRG neurons and investigate their role in itch and nociception.

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Autores principales:	Devin M. Barry, Xue-Ting Liu, Benlong Liu, Xian-Yu Liu, Fang Gao, Xiansi Zeng, Juan Liu, Qianyi Yang, Steven Wilhelm, Jun Yin, Ailin Tao, Zhou-Feng Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/53f793802fe24f6f9367fe8f40d917ea
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spelling	oai:doaj.org-article:53f793802fe24f6f9367fe8f40d917ea2021-12-02T16:49:43ZExploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors10.1038/s41467-020-15230-y2041-1723https://doaj.org/article/53f793802fe24f6f9367fe8f40d917ea2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15230-yhttps://doaj.org/toc/2041-1723The role of gastrin related peptide (GRP+) neurons in itch is debated. Here, the authors generate a conditional knock-in mouse to label and manipulate GRP expressing DRG neurons and investigate their role in itch and nociception.Devin M. BarryXue-Ting LiuBenlong LiuXian-Yu LiuFang GaoXiansi ZengJuan LiuQianyi YangSteven WilhelmJun YinAilin TaoZhou-Feng ChenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Devin M. Barry Xue-Ting Liu Benlong Liu Xian-Yu Liu Fang Gao Xiansi Zeng Juan Liu Qianyi Yang Steven Wilhelm Jun Yin Ailin Tao Zhou-Feng Chen Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors
description	The role of gastrin related peptide (GRP+) neurons in itch is debated. Here, the authors generate a conditional knock-in mouse to label and manipulate GRP expressing DRG neurons and investigate their role in itch and nociception.
format	article
author	Devin M. Barry Xue-Ting Liu Benlong Liu Xian-Yu Liu Fang Gao Xiansi Zeng Juan Liu Qianyi Yang Steven Wilhelm Jun Yin Ailin Tao Zhou-Feng Chen
author_facet	Devin M. Barry Xue-Ting Liu Benlong Liu Xian-Yu Liu Fang Gao Xiansi Zeng Juan Liu Qianyi Yang Steven Wilhelm Jun Yin Ailin Tao Zhou-Feng Chen
author_sort	Devin M. Barry
title	Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors
title_short	Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors
title_full	Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors
title_fullStr	Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors
title_full_unstemmed	Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors
title_sort	exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/53f793802fe24f6f9367fe8f40d917ea
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Exploration of sensory and spinal neurons expressing gastrin-releasing peptide in itch and pain related behaviors

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