Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections

Liu et al. investigate the mechanism for small colony variant (SCV) formation in Staphylococcus epidermidis and following genomic and metabolomic analysis, implicate a frame-shift mutation in glycine production as a potential cause of SCV formation. The authors also examine the effect of eDNA produc...

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Autores principales: Junlan Liu, Zhen Shen, Jin Tang, Qian Huang, Ying Jian, Yao Liu, Yanan Wang, Xiaowei Ma, Qian Liu, Lei He, Min Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/53fb26e60ba34110952de0e40c14adc8
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spelling oai:doaj.org-article:53fb26e60ba34110952de0e40c14adc82021-12-02T16:17:27ZExtracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections10.1038/s42003-021-02423-42399-3642https://doaj.org/article/53fb26e60ba34110952de0e40c14adc82021-07-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02423-4https://doaj.org/toc/2399-3642Liu et al. investigate the mechanism for small colony variant (SCV) formation in Staphylococcus epidermidis and following genomic and metabolomic analysis, implicate a frame-shift mutation in glycine production as a potential cause of SCV formation. The authors also examine the effect of eDNA production and biofilm formation.Junlan LiuZhen ShenJin TangQian HuangYing JianYao LiuYanan WangXiaowei MaQian LiuLei HeMin LiNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Junlan Liu
Zhen Shen
Jin Tang
Qian Huang
Ying Jian
Yao Liu
Yanan Wang
Xiaowei Ma
Qian Liu
Lei He
Min Li
Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections
description Liu et al. investigate the mechanism for small colony variant (SCV) formation in Staphylococcus epidermidis and following genomic and metabolomic analysis, implicate a frame-shift mutation in glycine production as a potential cause of SCV formation. The authors also examine the effect of eDNA production and biofilm formation.
format article
author Junlan Liu
Zhen Shen
Jin Tang
Qian Huang
Ying Jian
Yao Liu
Yanan Wang
Xiaowei Ma
Qian Liu
Lei He
Min Li
author_facet Junlan Liu
Zhen Shen
Jin Tang
Qian Huang
Ying Jian
Yao Liu
Yanan Wang
Xiaowei Ma
Qian Liu
Lei He
Min Li
author_sort Junlan Liu
title Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections
title_short Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections
title_full Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections
title_fullStr Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections
title_full_unstemmed Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections
title_sort extracellular dna released by glycine-auxotrophic staphylococcus epidermidis small colony variant facilitates catheter-related infections
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/53fb26e60ba34110952de0e40c14adc8
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