Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections
Liu et al. investigate the mechanism for small colony variant (SCV) formation in Staphylococcus epidermidis and following genomic and metabolomic analysis, implicate a frame-shift mutation in glycine production as a potential cause of SCV formation. The authors also examine the effect of eDNA produc...
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Nature Portfolio
2021
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oai:doaj.org-article:53fb26e60ba34110952de0e40c14adc82021-12-02T16:17:27ZExtracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections10.1038/s42003-021-02423-42399-3642https://doaj.org/article/53fb26e60ba34110952de0e40c14adc82021-07-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02423-4https://doaj.org/toc/2399-3642Liu et al. investigate the mechanism for small colony variant (SCV) formation in Staphylococcus epidermidis and following genomic and metabolomic analysis, implicate a frame-shift mutation in glycine production as a potential cause of SCV formation. The authors also examine the effect of eDNA production and biofilm formation.Junlan LiuZhen ShenJin TangQian HuangYing JianYao LiuYanan WangXiaowei MaQian LiuLei HeMin LiNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021) |
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EN |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Junlan Liu Zhen Shen Jin Tang Qian Huang Ying Jian Yao Liu Yanan Wang Xiaowei Ma Qian Liu Lei He Min Li Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections |
description |
Liu et al. investigate the mechanism for small colony variant (SCV) formation in Staphylococcus epidermidis and following genomic and metabolomic analysis, implicate a frame-shift mutation in glycine production as a potential cause of SCV formation. The authors also examine the effect of eDNA production and biofilm formation. |
format |
article |
author |
Junlan Liu Zhen Shen Jin Tang Qian Huang Ying Jian Yao Liu Yanan Wang Xiaowei Ma Qian Liu Lei He Min Li |
author_facet |
Junlan Liu Zhen Shen Jin Tang Qian Huang Ying Jian Yao Liu Yanan Wang Xiaowei Ma Qian Liu Lei He Min Li |
author_sort |
Junlan Liu |
title |
Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections |
title_short |
Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections |
title_full |
Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections |
title_fullStr |
Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections |
title_full_unstemmed |
Extracellular DNA released by glycine-auxotrophic Staphylococcus epidermidis small colony variant facilitates catheter-related infections |
title_sort |
extracellular dna released by glycine-auxotrophic staphylococcus epidermidis small colony variant facilitates catheter-related infections |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/53fb26e60ba34110952de0e40c14adc8 |
work_keys_str_mv |
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