Understanding racial disparities in severe maternal morbidity using Bayesian network analysis.
Previous studies have evaluated the marginal effect of various factors on the risk of severe maternal morbidity (SMM) using regression approaches. We add to this literature by utilizing a Bayesian network (BN) approach to understand the joint effects of clinical, demographic, and area-level factors....
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2021
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oai:doaj.org-article:5403236c92bd481b82549a95f0cdfc082021-12-02T20:19:10ZUnderstanding racial disparities in severe maternal morbidity using Bayesian network analysis.1932-620310.1371/journal.pone.0259258https://doaj.org/article/5403236c92bd481b82549a95f0cdfc082021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0259258https://doaj.org/toc/1932-6203Previous studies have evaluated the marginal effect of various factors on the risk of severe maternal morbidity (SMM) using regression approaches. We add to this literature by utilizing a Bayesian network (BN) approach to understand the joint effects of clinical, demographic, and area-level factors. We conducted a retrospective observational study using linked birth certificate and insurance claims data from the Arkansas All-Payer Claims Database (APCD), for the years 2013 through 2017. We used various learning algorithms and measures of arc strength to choose the most robust network structure. We then performed various conditional probabilistic queries using Monte Carlo simulation to understand disparities in SMM. We found that anemia and hypertensive disorder of pregnancy may be important clinical comorbidities to target in order to reduce SMM overall as well as racial disparities in SMM.Mandana RezaeiahariClare C BrownMir M AliJyotishka DattaJ Mick TilfordPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 10, p e0259258 (2021) |
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Medicine R Science Q Mandana Rezaeiahari Clare C Brown Mir M Ali Jyotishka Datta J Mick Tilford Understanding racial disparities in severe maternal morbidity using Bayesian network analysis. |
description |
Previous studies have evaluated the marginal effect of various factors on the risk of severe maternal morbidity (SMM) using regression approaches. We add to this literature by utilizing a Bayesian network (BN) approach to understand the joint effects of clinical, demographic, and area-level factors. We conducted a retrospective observational study using linked birth certificate and insurance claims data from the Arkansas All-Payer Claims Database (APCD), for the years 2013 through 2017. We used various learning algorithms and measures of arc strength to choose the most robust network structure. We then performed various conditional probabilistic queries using Monte Carlo simulation to understand disparities in SMM. We found that anemia and hypertensive disorder of pregnancy may be important clinical comorbidities to target in order to reduce SMM overall as well as racial disparities in SMM. |
format |
article |
author |
Mandana Rezaeiahari Clare C Brown Mir M Ali Jyotishka Datta J Mick Tilford |
author_facet |
Mandana Rezaeiahari Clare C Brown Mir M Ali Jyotishka Datta J Mick Tilford |
author_sort |
Mandana Rezaeiahari |
title |
Understanding racial disparities in severe maternal morbidity using Bayesian network analysis. |
title_short |
Understanding racial disparities in severe maternal morbidity using Bayesian network analysis. |
title_full |
Understanding racial disparities in severe maternal morbidity using Bayesian network analysis. |
title_fullStr |
Understanding racial disparities in severe maternal morbidity using Bayesian network analysis. |
title_full_unstemmed |
Understanding racial disparities in severe maternal morbidity using Bayesian network analysis. |
title_sort |
understanding racial disparities in severe maternal morbidity using bayesian network analysis. |
publisher |
Public Library of Science (PLoS) |
publishDate |
2021 |
url |
https://doaj.org/article/5403236c92bd481b82549a95f0cdfc08 |
work_keys_str_mv |
AT mandanarezaeiahari understandingracialdisparitiesinseverematernalmorbidityusingbayesiannetworkanalysis AT clarecbrown understandingracialdisparitiesinseverematernalmorbidityusingbayesiannetworkanalysis AT mirmali understandingracialdisparitiesinseverematernalmorbidityusingbayesiannetworkanalysis AT jyotishkadatta understandingracialdisparitiesinseverematernalmorbidityusingbayesiannetworkanalysis AT jmicktilford understandingracialdisparitiesinseverematernalmorbidityusingbayesiannetworkanalysis |
_version_ |
1718374223234203648 |