Metabolic syndrome: some results and prospects for solving the problem

Lifestyle changes associated with reduced physical activity, increased caloric content of food and a steady increase in emotional stress load cause potentiation of risk factors for cardiovascular disease. Metabolic syndrome combines hypertension, dyslipidemia, diabetes and obesity. Primary systemic...

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Autores principales:	X. Chu, O. Y. Kirgizova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2016
Materias:	metabolic syndrome cardiovascular diseases Science Q
Acceso en línea:	https://doaj.org/article/5404d04ab9754631b9128d2e34a0579b
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id	oai:doaj.org-article:5404d04ab9754631b9128d2e34a0579b
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spelling	oai:doaj.org-article:5404d04ab9754631b9128d2e34a0579b2021-11-23T06:14:35ZMetabolic syndrome: some results and prospects for solving the problem2541-94202587-959610.12737/23422https://doaj.org/article/5404d04ab9754631b9128d2e34a0579b2016-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/306https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Lifestyle changes associated with reduced physical activity, increased caloric content of food and a steady increase in emotional stress load cause potentiation of risk factors for cardiovascular disease. Metabolic syndrome combines hypertension, dyslipidemia, diabetes and obesity. Primary systemic insulin resistance and concomitant systemic hyperinsulinemia underlie the pathology. Insulin resistance triggers a vicious cycle of symptoms that lead to the emergence of severe cardiovascular complications. Metabolic cascade can also be initiated by obesity, which in its turn predisposes to the development of hypertension and reduction of the sensitivity of peripheral insulin receptors with subsequent accumulation of excess body weight. Treatment of metabolic syndrome should be pathogenetically substantiated and include antihypertensive, lipid-lowering, anti-thrombotic drugs on the background of a rational diet and lifestyle changes.X. ChuO. Y. KirgizovaScientific Сentre for Family Health and Human Reproduction Problemsarticlemetabolic syndromecardiovascular diseasesScienceQRUActa Biomedica Scientifica, Vol 1, Iss 5, Pp 187-194 (2016)
institution	DOAJ
collection	DOAJ
language	RU
topic	metabolic syndrome cardiovascular diseases Science Q
spellingShingle	metabolic syndrome cardiovascular diseases Science Q X. Chu O. Y. Kirgizova Metabolic syndrome: some results and prospects for solving the problem
description	Lifestyle changes associated with reduced physical activity, increased caloric content of food and a steady increase in emotional stress load cause potentiation of risk factors for cardiovascular disease. Metabolic syndrome combines hypertension, dyslipidemia, diabetes and obesity. Primary systemic insulin resistance and concomitant systemic hyperinsulinemia underlie the pathology. Insulin resistance triggers a vicious cycle of symptoms that lead to the emergence of severe cardiovascular complications. Metabolic cascade can also be initiated by obesity, which in its turn predisposes to the development of hypertension and reduction of the sensitivity of peripheral insulin receptors with subsequent accumulation of excess body weight. Treatment of metabolic syndrome should be pathogenetically substantiated and include antihypertensive, lipid-lowering, anti-thrombotic drugs on the background of a rational diet and lifestyle changes.
format	article
author	X. Chu O. Y. Kirgizova
author_facet	X. Chu O. Y. Kirgizova
author_sort	X. Chu
title	Metabolic syndrome: some results and prospects for solving the problem
title_short	Metabolic syndrome: some results and prospects for solving the problem
title_full	Metabolic syndrome: some results and prospects for solving the problem
title_fullStr	Metabolic syndrome: some results and prospects for solving the problem
title_full_unstemmed	Metabolic syndrome: some results and prospects for solving the problem
title_sort	metabolic syndrome: some results and prospects for solving the problem
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2016
url	https://doaj.org/article/5404d04ab9754631b9128d2e34a0579b
work_keys_str_mv	AT xchu metabolicsyndromesomeresultsandprospectsforsolvingtheproblem AT oykirgizova metabolicsyndromesomeresultsandprospectsforsolvingtheproblem
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Metabolic syndrome: some results and prospects for solving the problem

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