Visualization and quantification of APP intracellular domain-mediated nuclear signaling by bimolecular fluorescence complementation.
<h4>Background</h4>The amyloid precursor protein (APP) intracellular domain (AICD) is released from full-length APP upon sequential cleavage by either α- or β-secretase followed by γ-secretase. Together with the adaptor protein Fe65 and the histone acetyltransferase Tip60, AICD forms nuc...
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| Main Authors: | , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2013
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| Subjects: | |
| Online Access: | https://doaj.org/article/5407866b71174eafabc1cd7e9e47c6dd |
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