Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex

ABSTRACT Human immunodeficiency virus type 1 (HIV-1) Nef enhances virus replication and contributes to immune evasion in vivo, but the underlying molecular mechanisms remain incompletely defined. Nef interferes with host cell actin dynamics to restrict T lymphocyte responses to chemokine stimulation...

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Autores principales: Andrea Imle, Libin Abraham, Nikolaos Tsopoulidis, Bernard Hoflack, Kalle Saksela, Oliver T. Fackler
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://doaj.org/article/541c697a482f419082ce782f93454599
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