Entry of Polarized Effector Cells into Quiescence Forces HIV Latency

ABSTRACT The latent HIV reservoir is generated following HIV infection of activated effector CD4 T cells, which then transition to a memory phenotype. Here, we describe an ex vivo method, called QUECEL (quiescent effector cell latency), that mimics this process efficiently and allows production of l...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Curtis Dobrowolski, Saba Valadkhan, Amy C. Graham, Meenakshi Shukla, Angela Ciuffi, Amalio Telenti, Jonathan Karn
Format: article
Langue:EN
Publié: American Society for Microbiology 2019
Sujets:
Accès en ligne:https://doaj.org/article/541cf5d704a04c64a04abd20056f291a
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!