Biocatalytic production of adiponitrile and related aliphatic linear α,ω-dinitriles
Typically, preparation of the polymer precursors α,ω-dinitriles requires hydrogen cyanide. Here, the authors use aldoxime hydratase to produce adiponitrile and related aliphatic linear dinitriles under ambient conditions starting from readily available substrates without needing hydrogen cyanide.
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Nature Portfolio
2018
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oai:doaj.org-article:542a27835d1f47949ad6968f969e4f122021-12-02T16:50:11ZBiocatalytic production of adiponitrile and related aliphatic linear α,ω-dinitriles10.1038/s41467-018-07434-02041-1723https://doaj.org/article/542a27835d1f47949ad6968f969e4f122018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07434-0https://doaj.org/toc/2041-1723Typically, preparation of the polymer precursors α,ω-dinitriles requires hydrogen cyanide. Here, the authors use aldoxime hydratase to produce adiponitrile and related aliphatic linear dinitriles under ambient conditions starting from readily available substrates without needing hydrogen cyanide.Tobias BetkeManuel MaierHeidrun Gruber-WölflerHarald GrögerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
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Science Q Tobias Betke Manuel Maier Heidrun Gruber-Wölfler Harald Gröger Biocatalytic production of adiponitrile and related aliphatic linear α,ω-dinitriles |
description |
Typically, preparation of the polymer precursors α,ω-dinitriles requires hydrogen cyanide. Here, the authors use aldoxime hydratase to produce adiponitrile and related aliphatic linear dinitriles under ambient conditions starting from readily available substrates without needing hydrogen cyanide. |
format |
article |
author |
Tobias Betke Manuel Maier Heidrun Gruber-Wölfler Harald Gröger |
author_facet |
Tobias Betke Manuel Maier Heidrun Gruber-Wölfler Harald Gröger |
author_sort |
Tobias Betke |
title |
Biocatalytic production of adiponitrile and related aliphatic linear α,ω-dinitriles |
title_short |
Biocatalytic production of adiponitrile and related aliphatic linear α,ω-dinitriles |
title_full |
Biocatalytic production of adiponitrile and related aliphatic linear α,ω-dinitriles |
title_fullStr |
Biocatalytic production of adiponitrile and related aliphatic linear α,ω-dinitriles |
title_full_unstemmed |
Biocatalytic production of adiponitrile and related aliphatic linear α,ω-dinitriles |
title_sort |
biocatalytic production of adiponitrile and related aliphatic linear α,ω-dinitriles |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/542a27835d1f47949ad6968f969e4f12 |
work_keys_str_mv |
AT tobiasbetke biocatalyticproductionofadiponitrileandrelatedaliphaticlinearaōdinitriles AT manuelmaier biocatalyticproductionofadiponitrileandrelatedaliphaticlinearaōdinitriles AT heidrungruberwolfler biocatalyticproductionofadiponitrileandrelatedaliphaticlinearaōdinitriles AT haraldgroger biocatalyticproductionofadiponitrileandrelatedaliphaticlinearaōdinitriles |
_version_ |
1718383098406633472 |