Antibody-Dependent Cellular Cytotoxicity-Competent Antibodies against HIV-1-Infected Cells in Plasma from HIV-Infected Subjects

ABSTRACT Measuring Envelope (Env)-specific antibody (Ab)-dependent cellular cytotoxicity (ADCC)-competent Abs in HIV+ plasma is challenging because Env displays distinctive epitopes when present in a native closed trimeric conformation on infected cells or in a CD4-bound conformation on uninfected b...

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Autores principales: Franck P. Dupuy, Sanket Kant, Alexandre Barbé, Jean-Pierre Routy, Julie Bruneau, Bertrand Lebouché, Cécile Tremblay, Marzena Pazgier, Andrés Finzi, Nicole F. Bernard
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
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Acceso en línea:https://doaj.org/article/5431e290a44f41d0a90a711ffff01921
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