Cotransporter-mediated water transport underlying cerebrospinal fluid formation
Osmotic forces do not suffice to explain the rate of cerebrospinal fluid (CSF) production. Here, the authors show that the Na+/K+/2Cl− cotransporter in the choroid plexus contributes substantially to CSF production via its inherent ability to cotransport water.
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Nature Portfolio
2018
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oai:doaj.org-article:543501b1f622450685d52b070f2b2f832021-12-02T17:33:16ZCotransporter-mediated water transport underlying cerebrospinal fluid formation10.1038/s41467-018-04677-92041-1723https://doaj.org/article/543501b1f622450685d52b070f2b2f832018-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04677-9https://doaj.org/toc/2041-1723Osmotic forces do not suffice to explain the rate of cerebrospinal fluid (CSF) production. Here, the authors show that the Na+/K+/2Cl− cotransporter in the choroid plexus contributes substantially to CSF production via its inherent ability to cotransport water.Annette B. SteffensenEva K. OernboAnca StoicaNiklas J. GerkauDagne BarbuskaiteKaterina TritsarisChristine R. RoseNanna MacAulayNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Annette B. Steffensen Eva K. Oernbo Anca Stoica Niklas J. Gerkau Dagne Barbuskaite Katerina Tritsaris Christine R. Rose Nanna MacAulay Cotransporter-mediated water transport underlying cerebrospinal fluid formation |
| description |
Osmotic forces do not suffice to explain the rate of cerebrospinal fluid (CSF) production. Here, the authors show that the Na+/K+/2Cl− cotransporter in the choroid plexus contributes substantially to CSF production via its inherent ability to cotransport water. |
| format |
article |
| author |
Annette B. Steffensen Eva K. Oernbo Anca Stoica Niklas J. Gerkau Dagne Barbuskaite Katerina Tritsaris Christine R. Rose Nanna MacAulay |
| author_facet |
Annette B. Steffensen Eva K. Oernbo Anca Stoica Niklas J. Gerkau Dagne Barbuskaite Katerina Tritsaris Christine R. Rose Nanna MacAulay |
| author_sort |
Annette B. Steffensen |
| title |
Cotransporter-mediated water transport underlying cerebrospinal fluid formation |
| title_short |
Cotransporter-mediated water transport underlying cerebrospinal fluid formation |
| title_full |
Cotransporter-mediated water transport underlying cerebrospinal fluid formation |
| title_fullStr |
Cotransporter-mediated water transport underlying cerebrospinal fluid formation |
| title_full_unstemmed |
Cotransporter-mediated water transport underlying cerebrospinal fluid formation |
| title_sort |
cotransporter-mediated water transport underlying cerebrospinal fluid formation |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/543501b1f622450685d52b070f2b2f83 |
| work_keys_str_mv |
AT annettebsteffensen cotransportermediatedwatertransportunderlyingcerebrospinalfluidformation AT evakoernbo cotransportermediatedwatertransportunderlyingcerebrospinalfluidformation AT ancastoica cotransportermediatedwatertransportunderlyingcerebrospinalfluidformation AT niklasjgerkau cotransportermediatedwatertransportunderlyingcerebrospinalfluidformation AT dagnebarbuskaite cotransportermediatedwatertransportunderlyingcerebrospinalfluidformation AT katerinatritsaris cotransportermediatedwatertransportunderlyingcerebrospinalfluidformation AT christinerrose cotransportermediatedwatertransportunderlyingcerebrospinalfluidformation AT nannamacaulay cotransportermediatedwatertransportunderlyingcerebrospinalfluidformation |
| _version_ |
1718379998657642496 |