Immunomodulation and Antioxidant Activities as Possible Trypanocidal and Cardioprotective Mechanisms of Major Terpenes from <i>Lippia alba</i> Essential Oils in an Experimental Model of Chronic Chagas Disease

Immunomodulation and Antioxidant Activities as Possible Trypanocidal and Cardioprotective Mechanisms of Major Terpenes from <i>Lippia alba</i> Essential Oils in an Experimental Model of Chronic Chagas Disease

In the late phase of <i>Trypanosoma cruzi</i> infection, parasite persistence and an exaggerated immune response accompanied by oxidative stress play a crucial role in the genesis of Chronic Chagasic Cardiomyopathy (CCC). Current treatments (Benznidazole (BNZ) and Nifurtimox) can effect...

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Autores principales: Denerieth Ximena Espinel-Mesa, Clara Isabel González Rugeles, Julio César Mantilla Hernández, Elena E. Stashenko, Carlos Andrés Villegas-Lanau, John Jaime Quimbaya Ramírez, Liliana Torcoroma García Sánchez
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
chronic Chagas disease
<i>Trypanosoma cruzi</i>
antioxidant
immunomodulation
immunohistochemistry
essential oils
Therapeutics. Pharmacology
RM1-950
Acceso en línea:https://doaj.org/article/54438e7782a84e85b9b67dd0064f06bf
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