Mapping the electrostatic potential of the nucleosome acidic patch
Abstract The nucleosome surface contains an area with negative electrostatic potential known as the acidic patch, which functions as a binding platform for various proteins to regulate chromatin biology. The dense clustering of acidic residues may impact their effective pKa and thus the electronegat...
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Autores principales: | Heyi Zhang, Jelmer Eerland, Velten Horn, Raymond Schellevis, Hugo van Ingen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/544c1de6121f412da6043bec52db0a82 |
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