Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE

The mechanisms involved in SLC4-mediated ion transport are still under debate. Here, the authors present a cryoEM structure of the Sodium-driven Chloride/Bicarbonate Exchanger NDCBE, which - together with computational modeling and mutagenesis - reveals molecular determinants of ion transport by SLC...

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Autores principales:	Weiguang Wang, Kirill Tsirulnikov, Hristina R. Zhekova, Gülru Kayık, Hanif Muhammad Khan, Rustam Azimov, Natalia Abuladze, Liyo Kao, Debbie Newman, Sergei Yu. Noskov, Z. Hong Zhou, Alexander Pushkin, Ira Kurtz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/5450105e6774470bbdbd14557832e365
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spelling	oai:doaj.org-article:5450105e6774470bbdbd14557832e3652021-12-02T17:37:41ZCryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE10.1038/s41467-021-25998-22041-1723https://doaj.org/article/5450105e6774470bbdbd14557832e3652021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25998-2https://doaj.org/toc/2041-1723The mechanisms involved in SLC4-mediated ion transport are still under debate. Here, the authors present a cryoEM structure of the Sodium-driven Chloride/Bicarbonate Exchanger NDCBE, which - together with computational modeling and mutagenesis - reveals molecular determinants of ion transport by SLC4.Weiguang WangKirill TsirulnikovHristina R. ZhekovaGülru KayıkHanif Muhammad KhanRustam AzimovNatalia AbuladzeLiyo KaoDebbie NewmanSergei Yu. NoskovZ. Hong ZhouAlexander PushkinIra KurtzNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Weiguang Wang Kirill Tsirulnikov Hristina R. Zhekova Gülru Kayık Hanif Muhammad Khan Rustam Azimov Natalia Abuladze Liyo Kao Debbie Newman Sergei Yu. Noskov Z. Hong Zhou Alexander Pushkin Ira Kurtz Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE
description	The mechanisms involved in SLC4-mediated ion transport are still under debate. Here, the authors present a cryoEM structure of the Sodium-driven Chloride/Bicarbonate Exchanger NDCBE, which - together with computational modeling and mutagenesis - reveals molecular determinants of ion transport by SLC4.
format	article
author	Weiguang Wang Kirill Tsirulnikov Hristina R. Zhekova Gülru Kayık Hanif Muhammad Khan Rustam Azimov Natalia Abuladze Liyo Kao Debbie Newman Sergei Yu. Noskov Z. Hong Zhou Alexander Pushkin Ira Kurtz
author_facet	Weiguang Wang Kirill Tsirulnikov Hristina R. Zhekova Gülru Kayık Hanif Muhammad Khan Rustam Azimov Natalia Abuladze Liyo Kao Debbie Newman Sergei Yu. Noskov Z. Hong Zhou Alexander Pushkin Ira Kurtz
author_sort	Weiguang Wang
title	Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE
title_short	Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE
title_full	Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE
title_fullStr	Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE
title_full_unstemmed	Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE
title_sort	cryo-em structure of the sodium-driven chloride/bicarbonate exchanger ndcbe
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5450105e6774470bbdbd14557832e365
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Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE

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