Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics

López-González et al study the fMRI brain dynamics and their underlying mechanism from patients that suffered brain injuries leading to a disorder of consciousness as well as from healthy subjects undergoing propofol-induced sedation. They show that pathological and pharmacological low-level states...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ane López-González, Rajanikant Panda, Adrián Ponce-Alvarez, Gorka Zamora-López, Anira Escrichs, Charlotte Martial, Aurore Thibaut, Olivia Gosseries, Morten L. Kringelbach, Jitka Annen, Steven Laureys, Gustavo Deco
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Accès en ligne:https://doaj.org/article/5455e3476f9844c49701d43bf6d7d548
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
Description
Résumé:López-González et al study the fMRI brain dynamics and their underlying mechanism from patients that suffered brain injuries leading to a disorder of consciousness as well as from healthy subjects undergoing propofol-induced sedation. They show that pathological and pharmacological low-level states of consciousness display disrupted synchronization patterns, higher constraint to the anatomy and a loss of heterogeneity and stability in the structural hubs compared to conscious states.