Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics

López-González et al study the fMRI brain dynamics and their underlying mechanism from patients that suffered brain injuries leading to a disorder of consciousness as well as from healthy subjects undergoing propofol-induced sedation. They show that pathological and pharmacological low-level states...

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Autores principales:	Ane López-González, Rajanikant Panda, Adrián Ponce-Alvarez, Gorka Zamora-López, Anira Escrichs, Charlotte Martial, Aurore Thibaut, Olivia Gosseries, Morten L. Kringelbach, Jitka Annen, Steven Laureys, Gustavo Deco
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/5455e3476f9844c49701d43bf6d7d548
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spelling	oai:doaj.org-article:5455e3476f9844c49701d43bf6d7d5482021-12-02T17:41:16ZLoss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics10.1038/s42003-021-02537-92399-3642https://doaj.org/article/5455e3476f9844c49701d43bf6d7d5482021-09-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02537-9https://doaj.org/toc/2399-3642López-González et al study the fMRI brain dynamics and their underlying mechanism from patients that suffered brain injuries leading to a disorder of consciousness as well as from healthy subjects undergoing propofol-induced sedation. They show that pathological and pharmacological low-level states of consciousness display disrupted synchronization patterns, higher constraint to the anatomy and a loss of heterogeneity and stability in the structural hubs compared to conscious states.Ane López-GonzálezRajanikant PandaAdrián Ponce-AlvarezGorka Zamora-LópezAnira EscrichsCharlotte MartialAurore ThibautOlivia GosseriesMorten L. KringelbachJitka AnnenSteven LaureysGustavo DecoNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Ane López-González Rajanikant Panda Adrián Ponce-Alvarez Gorka Zamora-López Anira Escrichs Charlotte Martial Aurore Thibaut Olivia Gosseries Morten L. Kringelbach Jitka Annen Steven Laureys Gustavo Deco Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics
description	López-González et al study the fMRI brain dynamics and their underlying mechanism from patients that suffered brain injuries leading to a disorder of consciousness as well as from healthy subjects undergoing propofol-induced sedation. They show that pathological and pharmacological low-level states of consciousness display disrupted synchronization patterns, higher constraint to the anatomy and a loss of heterogeneity and stability in the structural hubs compared to conscious states.
format	article
author	Ane López-González Rajanikant Panda Adrián Ponce-Alvarez Gorka Zamora-López Anira Escrichs Charlotte Martial Aurore Thibaut Olivia Gosseries Morten L. Kringelbach Jitka Annen Steven Laureys Gustavo Deco
author_facet	Ane López-González Rajanikant Panda Adrián Ponce-Alvarez Gorka Zamora-López Anira Escrichs Charlotte Martial Aurore Thibaut Olivia Gosseries Morten L. Kringelbach Jitka Annen Steven Laureys Gustavo Deco
author_sort	Ane López-González
title	Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics
title_short	Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics
title_full	Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics
title_fullStr	Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics
title_full_unstemmed	Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics
title_sort	loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/5455e3476f9844c49701d43bf6d7d548
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Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics

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