Homotaurine limits the spreading of T cell autoreactivity within the CNS and ameliorates disease in a model of multiple sclerosis
Abstract Most multiple sclerosis (MS) patients given currently available disease-modifying drugs (DMDs) experience progressive disability. Accordingly, there is a need for new treatments that can limit the generation of new waves T cell autoreactivity that drive disease progression. Notably, immune...
Guardado en:
Autores principales: | Jide Tian, Min Song, Daniel L. Kaufman |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/5457f0c20d684103869242c6aa9fbc87 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
A beta-lactam antibiotic dampens excitotoxic inflammatory CNS damage in a mouse model of multiple sclerosis.
por: Nico Melzer, et al.
Publicado: (2008) -
Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis
por: Sarah K. Williams, et al.
Publicado: (2018) -
Identification of autoreactive B cells with labeled nucleosomes
por: Vincent Gies, et al.
Publicado: (2017) -
Primary Peripheral Epstein-Barr Virus Infection Can Lead to CNS Infection and Neuroinflammation in a Rabbit Model: Implications for Multiple Sclerosis Pathogenesis
por: Asma Hassani, et al.
Publicado: (2021) -
CNS drugs
Publicado: (1994)